Transmission of COVID-19 in 282 clusters in Catalonia, Spain: a cohort study

This article has been Reviewed by the following groups

Read the full article See related articles

Abstract

No abstract available

Article activity feed

  1. SciScore for 10.1101/2020.10.27.20220277: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    Institutional Review Board StatementIRB: The study protocol of the BCN PEP CoV-2 Study was approved by the ethics committee of Hospital Germans Trias Pujol, (Badalona, Spain).
    Consent: Written informed consent was obtained from all participants.
    Randomizationnot detected.
    Blindingnot detected.
    Power Analysisnot detected.
    Sex as a biological variablenot detected.

    Table 2: Resources

    No key resources detected.


    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).


    Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
    The study has several limitations. First, asymptomatic people were not enrolled as index cases, affecting our ability to fully characterize all types of transmission chain. Second, we did not find any evidence of decreased risk of transmission in individuals who reported mask use. While this finding collides with the evidence reported elsewhere,8 we did not have fine-grained data on type of mask (surgical vs FFP2), use of other measures of PPE or other infection control practices, thus limiting our ability to make clear inferences about the impact of PPE on transmission risk. Mask usage is likely correlated with type of exposure which might further confound associations but we did not note any association between mask use and risk either in our unadjusted analysis (Table 3) or in a multivariable model excluding type of exposure (data not shown). Third, we used time to symptom onset (with later confirmation of infection) rather than time to positive PCR test based on serial testing. Nonetheless, accurate calculation of the incubation period was feasible because of the prospective nature of the study, accurate identification of exposure by face-to-face interview, and intensive active and passive monitoring of exposed contacts. We followed participants over 14-day periods, thus incubation periods beyond 14 days may not have been detected. Within each cluster we cannot be completely certain about the directionality of transmission, but our inclusion criteria including the absence...

    Results from TrialIdentifier: We found the following clinical trial numbers in your paper:

    IdentifierStatusTitle
    NCT04304053CompletedTreatment of COVID-19 Cases and Chemoprophylaxis of Contacts…


    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.


    Results from JetFighter: We did not find any issues relating to colormaps.


    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    About SciScore

    SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore checks for the presence and correctness of RRIDs (research resource identifiers), and for rigor criteria such as sex and investigator blinding. For details on the theoretical underpinning of rigor criteria and the tools shown here, including references cited, please follow this link.