Effectiveness of isolation, testing, contact tracing, and physical distancing on reducing transmission of SARS-CoV-2 in different settings: a mathematical modelling study
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Abstract
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SciScore for 10.1101/2020.04.23.20077024: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
NIH rigor criteria are not applicable to paper type.Table 2: Resources
No key resources detected.
Results from OddPub: Thank you for sharing your code and data.
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:Our analysis has several limitations. We focused on individual-level transmission between a primary case and their contacts, rather than considering higher degree network effects. If contacts were clustered (i.e. know each other), it could reduce the number of contacts that need to be traced over multiple generations of transmission. We also assumed that contacts made within the home are the same people daily, but contacts outside home …
SciScore for 10.1101/2020.04.23.20077024: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
NIH rigor criteria are not applicable to paper type.Table 2: Resources
No key resources detected.
Results from OddPub: Thank you for sharing your code and data.
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:Our analysis has several limitations. We focused on individual-level transmission between a primary case and their contacts, rather than considering higher degree network effects. If contacts were clustered (i.e. know each other), it could reduce the number of contacts that need to be traced over multiple generations of transmission. We also assumed that contacts made within the home are the same people daily, but contacts outside home are made independently each day. Repeated contacts would also reduce the number that need to be traced. However, our estimates are consistent with the upper bound of numbers traced in empirical studies (Table 1), as well as analysis of UK social interactions that accounts for higher degree contacts (14). Because our data was not stratified beyond the four contact settings we considered (home, work, school, other), we could not consider further specific settings, e.g. mass gatherings. However, our finding that gatherings in other settings needed to be restricted to relatively small sizes before there was a noticeable impact on transmission is consistent with findings that groups between 10–50 people have a larger impact on SARS-CoV-2 dynamics than groups of more than 50 (28). Our baseline assumptions were plausible but optimistic. In particular, we assume a delay of symptom onset to isolation of 2.6 days in the baseline scenario, and quarantine that was sufficiently fast to prevent any onwards transmission among successfully traced contacts, wit...
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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