Seroprevalence of anti-SARS-CoV-2 IgG antibodies in Geneva, Switzerland (SEROCoV-POP): a population-based study
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SciScore for 10.1101/2020.05.02.20088898: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement Potential participants then received a confirmation by email, which included a link to a questionnaire and a consent form to complete at home and bring on the day of the study visit. Randomization Methods Study Design Each week, ~1300 randomly selected previous participants of the Bus Santé study with an email address on file (n~10’072, Figure S1) were invited to participate in the SEROCoV-POP study by email, which provided a link to an online appointment booking system for a visit at one of two sites within the proceeding seven days. Blinding not detected. Power Analysis not detected. Sex as a biological variable Results: In the first three weeks, we … SciScore for 10.1101/2020.05.02.20088898: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement Potential participants then received a confirmation by email, which included a link to a questionnaire and a consent form to complete at home and bring on the day of the study visit. Randomization Methods Study Design Each week, ~1300 randomly selected previous participants of the Bus Santé study with an email address on file (n~10’072, Figure S1) were invited to participate in the SEROCoV-POP study by email, which provided a link to an online appointment booking system for a visit at one of two sites within the proceeding seven days. Blinding not detected. Power Analysis not detected. Sex as a biological variable Results: In the first three weeks, we enrolled 1335 participants coming from 633 households, with 16% <20 years of age and 53.6% female, a distribution similar to that of Geneva. Table 2: Resources
Antibodies Sentences Resources We tested each participant for antiSARS-CoV-2-IgG antibodies using a commercially available enzyme-linked immunosorbent assay (Euroimmun AG, Lübeck, Germany). antiSARS-CoV-2-IgGsuggested: NoneLaboratory Analyses We assessed anti-SARS-CoV-2-IgG antibodies using a commercially available enzyme-linked immunosorbent assay (Euroimmun AG, Lübeck, Germany # EI 2606-9601 G) targeting the S1-domain of the spike protein of SARS-CoV-2; sera diluted 1:101 were processed on a EuroLabWorkstation ELISA. anti-SARS-CoV-2-IgGsuggested: NoneFurther, we show that three weeks after the peak of confirmed cases, only 1 in 10 people has developed antibodies against SARS-CoV-2, even in one of the more heavily affected areas in Europe 13. SARS-CoV-2suggested: (Sino Biological Cat# 40143-R019, AB_2827973)To our knowledge, this is the first study to perform a large-scale seroprevalence survey of anti-SARSCoV-2 IgG antibodies where participants were selected from a representative sample of the general population. anti-SARSCoV-2 IgGsuggested: NoneResults from OddPub: We did not find a statement about open data. We also did not find a statement about open code. Researchers are encouraged to share open data when possible (see Nature blog).
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