Correlation between Chest Computed Tomography and Lung Ultrasonography in Patients with Coronavirus Disease 2019 (COVID-19)
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SciScore for 10.1101/2020.05.08.20095117: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement IRB: The study was conducted in accordance with the Declaration of Helsinki, and was approved by the Research Ethics Committee of our University Hospital (PI-4089).
Consent: Informed consent was obtained from each enrolled patient.Randomization not detected. Blinding Two radiologist trainees with 2–4 years of experiences (S.A and R.A.) reviewed all images independently blinded to the clinical information, supervised by a senior radiologist with more than 10 years of experience (M.M.G). Power Analysis The sample size for correlation was calculated to detect a 20% of difference between LUS and CT findings, assuming a 95% confidence interval (CI) and power of 80%. Sex … SciScore for 10.1101/2020.05.08.20095117: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement IRB: The study was conducted in accordance with the Declaration of Helsinki, and was approved by the Research Ethics Committee of our University Hospital (PI-4089).
Consent: Informed consent was obtained from each enrolled patient.Randomization not detected. Blinding Two radiologist trainees with 2–4 years of experiences (S.A and R.A.) reviewed all images independently blinded to the clinical information, supervised by a senior radiologist with more than 10 years of experience (M.M.G). Power Analysis The sample size for correlation was calculated to detect a 20% of difference between LUS and CT findings, assuming a 95% confidence interval (CI) and power of 80%. Sex as a biological variable not detected. Table 2: Resources
Software and Algorithms Sentences Resources Statistical analyses were conducted with IBM SPSS software v20.0 SPSSsuggested: (SPSS, RRID:SCR_002865)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:Due to its limitations, diagnostic imaging plays a key role in the management of these patients. A study of 1049 patients undergoing chest CT scan and RT-PCR testing determined that CT abnormalities had a highly sensitivity for diagnosis of COVID-19 patients (1), suggesting that CT scan should be considered as a screening tool, especially in epidemic areas with high pre-test probability. Therefore in many centers CT scans have been replaced for chest X-ray. However, the use of CT scan in the ED has many limitations, such as the radiation exposure, especially for mild illness, the low availability and the contraindication of its use in unstable patients. Also, we found a proportion of normal chest CT that is relatively high (27.4%), but similar to those previously reported (30.8%) (9). Preliminary reports in COVID-19 era, suggest there is a correlation of LUS findings to those of the CT scan (14-15). These reports have characterized LUS findings in COVID-19 patients. Moreover, Soldati et al (16) have proposed a standardized approach to performing LUS in these patients, including a 14-zone technique, and a scoring system to quantify severity of lung involvement. Although we agree there should be a consensus in the LUS exam method, the 12-zone is more extended and validated (12). There have been reports regarding the cardiac injury in COVID-19 patients that ranges from 7.2%-14% (17-18). In our study, we found one young patient that had a normal LUS exam, which prompted a sonogra...
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
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- No protocol registration statement was detected.
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