Differentiating COVID-19 and dengue from other febrile illnesses in co-epidemics: Development and internal validation of COVIDENGUE scores
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SciScore for 10.1101/2021.10.14.21264897: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics Consent: Adults, as well as children under the age of 18 years (having the additional verbal consent of their parent or legal guardian) who expressed no opposition were asked to answer a questionnaire and were personally interviewed by a nurse in accordance with the French legislation on bioethics for retrospective research. Sex as a biological variable not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Table 2: Resources
Software and Algorithms Sentences Resources Bivariable and multivariable multinomial logistic regression (MLR) models were fitted within Stata14® (Statacorp, College Station, Texas, USA) to identify independent predictors of COVID-19 and … SciScore for 10.1101/2021.10.14.21264897: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics Consent: Adults, as well as children under the age of 18 years (having the additional verbal consent of their parent or legal guardian) who expressed no opposition were asked to answer a questionnaire and were personally interviewed by a nurse in accordance with the French legislation on bioethics for retrospective research. Sex as a biological variable not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Table 2: Resources
Software and Algorithms Sentences Resources Bivariable and multivariable multinomial logistic regression (MLR) models were fitted within Stata14® (Statacorp, College Station, Texas, USA) to identify independent predictors of COVID-19 and dengue using OFIs as controls. Statacorpsuggested: NoneResults from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:Strengths and limitations: A scoring system should have both construct and content validity. It must be able to be reproduced over time and across geographic and methodological boundaries. It must also be accurate (calibration and discrimination) and clinically meaningful [19]. Before this study, we previously assumed that COVID-19 and dengue diagnoses could be affected by a misclassification bias which could stem from the poor sensitivity of both SARS-CoV-2 molecular and DENV NS1 antigen tests rather than from their false positives [9]. This putative bias was believed to be minimal given that, firstly, on Reunion Island, like anywhere else during the rise of the COVID-19 pandemic [20], there was little cocirculation of other respiratory viruses that could have competed with SARS-CoV-2 and caused false negatives, [21] and secondly, for COVID-19, negative samples were retested by RT-PCR upon onset of new symptoms, meaning that rapid antibody or antigenic tests were ruled out, while for dengue, the workup was completed by a RT-PCR or a serology test to downsize false negative and false positive proportions [22-24]. This caution decision rule likely pledges the diagnostic accuracy of our gold standards. Interestingly, the calibration of both scores was satisfactory to excellent and displayed measures close to the theoretical model from which they were derived based on a set of various goodness-of-fit metrics. Notwithstanding a relatively small study population, the diagnostic ac...
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- No funding statement was detected.
- No protocol registration statement was detected.
Results from scite Reference Check: We found no unreliable references.
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