Catching a resurgence: Increase in SARS-CoV-2 viral RNA identified in wastewater 48 h before COVID-19 clinical tests and 96 h before hospitalizations
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SciScore for 10.1101/2020.11.22.20236554: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
No key resources detected.
Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:This could signify that hospitalizations may begin peaking four days after an increased viral RNA signal, with the caveat that hospitalizations rates may be significantly higher when viral RNA signal is the result from shedding …
SciScore for 10.1101/2020.11.22.20236554: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
No key resources detected.
Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:This could signify that hospitalizations may begin peaking four days after an increased viral RNA signal, with the caveat that hospitalizations rates may be significantly higher when viral RNA signal is the result from shedding of an at-risk population group (young infants, elderly, immunocompromised, etc.). In addition, the RNA signal post-resurgence indicates that the resurgence events in viral RNA signal serves to weaken the correlation of subsequent peaks with clinical testing metrics. It is hypothesized that early and later infections and overlapping shedding events of duration and intensity convolute peaks within a period of time following the initial new peaks/surges in COVID-19 infections. Nonetheless, the RNA epidemiological metric of copies/copies PMMoV may become extremely valuable to public health units in their preparation for the next COVID-19 wave.
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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