C-Reactive protein and SOFA scale: A simple score as early predictor of critical care requirement in patients with COVID-19 pneumonia in Spain
This article has been Reviewed by the following groups
Listed in
- Evaluated articles (ScreenIT)
Abstract
No abstract available
Article activity feed
-
-
SciScore for 10.1101/2020.05.22.20110429: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement IRB: This study was approved by the Research Ethics Commission of the clinical hospital of Salamanca (PI 2020 05 487) and the requirement for informed consent was waived by the Ethics Commission.
Consent: This study was approved by the Research Ethics Commission of the clinical hospital of Salamanca (PI 2020 05 487) and the requirement for informed consent was waived by the Ethics Commission.Randomization Seventy-five patients were randomly selected from those admitted to the critical care units within the University Hospital of Salamanca (Critical care group (CG)) between March 15 to April 15, 2020. Blinding not detected. Power Analysis not detected. Sex as a … SciScore for 10.1101/2020.05.22.20110429: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement IRB: This study was approved by the Research Ethics Commission of the clinical hospital of Salamanca (PI 2020 05 487) and the requirement for informed consent was waived by the Ethics Commission.
Consent: This study was approved by the Research Ethics Commission of the clinical hospital of Salamanca (PI 2020 05 487) and the requirement for informed consent was waived by the Ethics Commission.Randomization Seventy-five patients were randomly selected from those admitted to the critical care units within the University Hospital of Salamanca (Critical care group (CG)) between March 15 to April 15, 2020. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Software and Algorithms Sentences Resources SPSS 21® and Stata 15® were used to perform the statistical analysis. SPSSsuggested: (SPSS, RRID:SCR_002865)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:Our study has some limitations, because of the retrospective nature as well as because some laboratory tests were missing in some patients.. Although the sample size is rather small, the inclusion of randomly adult patients COVID-19 positive is representative of the number of cases treated in critical care units. Finally, overall and as expected, patients that required admission into the critical care units had a significantly higher inpatient mortality rate, more than twice, compared to those who did not require it. The mortality rate here reported is consistent with that reported in other series (3) and based on this fact, it results crucial the potential identification of this group of patients at the moment of admission. As patients presenting with a SOFA score >2 plus high levels of CRP will more likely require critical care, further actions could be implemented in order to reduce the requirement of critical care in these patients with the final objective of decreasing the inpatient mortality rate.
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
-
