Predictors of severe symptomatic laboratory-confirmed SARS-CoV-2 reinfection
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SciScore for 10.1101/2020.10.14.20212720: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
No key resources detected.
Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:The potential limitations of this study must be cited. First, the utilized definition of severe COVID-19 in our study represents a limitation that must be cited given that no laboratory-related data (e.g. PaO2) was collected. …
SciScore for 10.1101/2020.10.14.20212720: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
No key resources detected.
Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:The potential limitations of this study must be cited. First, the utilized definition of severe COVID-19 in our study represents a limitation that must be cited given that no laboratory-related data (e.g. PaO2) was collected. However, a meta-analysis including 15 studies evidenced that dyspnea is a stand-alone prognostic factor of COVID-19-related mortality [9]. Besides, and according to normative standards that have been followed since the beginning of the pandemic in Mexico, hospitalization criteria include the use of validated scales as PSI (Pneumonia Severity Index) and CURB-65 (Confusion, Urea level, Respiratory rate, Blood pressure, and age ≥ 65) [10]. Therefore, this severity indicator seems to be plausible in the study population. Second, since no mass screening has been performed in Mexico, we were unable to identify second-time asymptomatic cases of SARS-COV-2 infection. Moreover, an undetermined fraction of patients that are currently being identified as primary COVID-19 may correspond to subsequent infections and the related public health implications are unknown.
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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SciScore for 10.1101/2020.10.14.20212720: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
No key resources detected.
Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
The potential limitations of this study must be cited. First, the utilized definition of severe COVID-19 in our study represents a limitation that must be cited given that no laboratoryrelated data (e.g. PaO2) was collected. …
SciScore for 10.1101/2020.10.14.20212720: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
No key resources detected.
Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
The potential limitations of this study must be cited. First, the utilized definition of severe COVID-19 in our study represents a limitation that must be cited given that no laboratoryrelated data (e.g. PaO2) was collected. However, a meta-analysis including 15 studies evidenced that dyspnea is a stand-alone prognostic factor of COVID-19-related mortality [9]. Besides, and according to normative standards that have been followed since the beginning of the pandemic in Mexico, hospitalization criteria include the use of validated scales as PSI (Pneumonia Severity Index) and CURB-65 (Confusion, Urea level, Respiratory rate, Blood pressure, and age ≥ 65) [10]. Therefore, this severity indicator seems to be plausible in the study population. Second, since no mass screening has been performed in Mexico, we were unable to identify second-time asymptomatic cases of SARS-COV-2 infection. Moreover, an undetermined fraction of patients that are currently being identified as primary COVID-19 may correspond to subsequent infections and the related public health implications are unknown.
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
About SciScore
SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore checks for the presence and correctness of RRIDs (research resource identifiers), and for rigor criteria such as sex and investigator blinding. For details on the theoretical underpinning of rigor criteria and the tools shown here, including references cited, please follow this link.
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SciScore for 10.1101/2020.09.28.20203190: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Cell Line Authentication not detected. Table 2: Resources
Experimental Models: Cell Lines Sentences Resources We performed a nationwide retrospective cohort study in Mexico, including adults (aged 20 years or above) with laboratory-confirmed COVID-19 (quantitative reverse transcription-polymerase chain reaction, RT-qPCR) COVID-19 by SARS-COV-2. COVID-19suggested: NoneResults from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from Lim…SciScore for 10.1101/2020.09.28.20203190: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Cell Line Authentication not detected. Table 2: Resources
Experimental Models: Cell Lines Sentences Resources We performed a nationwide retrospective cohort study in Mexico, including adults (aged 20 years or above) with laboratory-confirmed COVID-19 (quantitative reverse transcription-polymerase chain reaction, RT-qPCR) COVID-19 by SARS-COV-2. COVID-19suggested: NoneResults from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
-