30-day mortality in patients hospitalized with COVID-19 during the first wave of the Italian epidemic: A prospective cohort study
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SciScore for 10.1101/2020.05.02.20088336: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement Consent: Informed consent was waived in the case of patients undergoing mechanical ventilation upon admission. Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Software and Algorithms Sentences Resources All of the statistical analyses were made using SAS software, version 9.4, and differences with P values of <0.05 were considered statistically significant. SASsuggested: (SASqPCR, RRID:SCR_003056)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationReco…SciScore for 10.1101/2020.05.02.20088336: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement Consent: Informed consent was waived in the case of patients undergoing mechanical ventilation upon admission. Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Software and Algorithms Sentences Resources All of the statistical analyses were made using SAS software, version 9.4, and differences with P values of <0.05 were considered statistically significant. SASsuggested: (SASqPCR, RRID:SCR_003056)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:Our study has a number of limitations. Firstly, as in China, the dramatically evolving scenario of the epidemic in Italy required continuous structural, organisational and staff changes that exposed the study to maturation bias. In particular, the number of laboratory examinations performed upon admission was limited (i.e. Interleukine-6 determination became available only after 15 days from the start of the study). Secondly, only 14.8% of our patients underwent a chest computed tomography upon admission because of barriers in our infrastructure created in order to ensure a dedicated COVID-19 service. Thirdly, it was difficult to ascertain the different effects on outcomes of the miscellaneous and often concomitant drug treatments given to our patients because of the absence of a standard of care for COVID-19 (excluding oxygen supplementation). Nevertheless, as all of the patients admitted to our Infectious Diseases Department were enrolled in this study and the study population was probably representative of the COVID-19 patients hospitalised in Italy in the early stage of the epidemic.
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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