A critical update on the role of mild and serious vitamin D deficiency prevalence and the COVID-19 epidemic in Europe

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Abstract

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  1. SciScore for 10.1101/2021.03.04.21252885: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    Institutional Review Board Statementnot detected.
    Randomizationnot detected.
    Blindingnot detected.
    Power Analysisnot detected.
    Sex as a biological variableConference proceedings, editorials, commentaries, book chapters/book reviews and studies confined to selective sample of community-dwelling people, such as pregnant women, menopausal women and patients with diagnosed illnesses were excluded.

    Table 2: Resources

    Software and Algorithms
    SentencesResources
    Data on the prevalence of Vit D deficiency among these countries were extracted by conducting a comprehensive electronic search in PubMed® database (up to February 6th 2021).
    PubMed®
    suggested: (PubMed, RRID:SCR_004846)

    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).


    Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
    Among the limitations of our study is that the data on prevalence of Vit D deficiency of the countries included was not generated from national level surveys. Therefore, the very recently published studies (including data only from the last decade) with the most representative sample for each country’s population were carefully selected for our analysis. As described in our Methods, screened studies were limited to adults (≥18 years), as the severity of COVID-19 infections among children has been rather mild.65 More detailed data regarding neither COVID-19 infection rates per age nor age distribution for each country was available, and therefore correlations for these subgroups could not be performed. Governments should implement proper preventive measures to increase awareness among the populations on the risk of Vit D deficiency rather than on its role in during the COVID-19 pandemic. Vit D supplementation should be advised only for those belonging to a high risk group of deficiency, such as new-borns, toddlers, pregnant women, elderly as well as non-Western immigrants,66 always under medical supervision and not as a preventive factor of COVID-19 infection. There might be several on-going randomized controlled trials (RCTs) examining the vitamin D supplementation in COVID-19 patients,67 however until there are solid data available from well-designed RCTs that will allow us to take relevant clinical decisions, the supplementation of Vit D as a way to prevent infection or imp...

    Results from TrialIdentifier: No clinical trial numbers were referenced.


    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.


    Results from JetFighter: We did not find any issues relating to colormaps.


    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    About SciScore

    SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore checks for the presence and correctness of RRIDs (research resource identifiers), and for rigor criteria such as sex and investigator blinding. For details on the theoretical underpinning of rigor criteria and the tools shown here, including references cited, please follow this link.

  2. SciScore for 10.1101/2021.01.28.21250673: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    Institutional Review Board Statementnot detected.
    Randomizationnot detected.
    Blindingnot detected.
    Power Analysisnot detected.
    Sex as a biological variableIn addition, conference proceedings, editorials, commentaries, book chapters/book reviews and studies confined to selective sample of community-dwelling people, such as pregnant women, elderly people, and patients with diagnosed illnesses were excluded.

    Table 2: Resources

    Software and Algorithms
    SentencesResources
    Data on the prevalence of Vit D deficiency among these countries were extracted by conducting a comprehensive electronic search in PubMed® database.
    PubMed®
    suggested: (PubMed, RRID:SCR_004846)

    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).


    Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.

    Results from TrialIdentifier: No clinical trial numbers were referenced.


    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.


    Results from JetFighter: We did not find any issues relating to colormaps.


    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    About SciScore

    SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore checks for the presence and correctness of RRIDs (research resource identifiers), and for rigor criteria such as sex and investigator blinding. For details on the theoretical underpinning of rigor criteria and the tools shown here, including references cited, please follow this link.