Investigating the conformational dynamics of SARS-CoV-2 NSP6 protein with emphasis on non-transmembrane 91–112 & 231–290 regions
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SciScore for 10.1101/2021.07.06.451329: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
NIH rigor criteria are not applicable to paper type.Table 2: Resources
Software and Algorithms Sentences Resources We have utilized Charmm36m forcefield in Gromacs v5 on high performance cluster (HPC) of IIT Mandi, where simulation setup was built by placing the protein structure (NSP6 91-112 and NSP6-CTR) in a cubic box with a distance of 10Å from each edge along with SPC water model and 0.15M NaCl salt concentration. Gromacssuggested: (GROMACS, RRID:SCR_014565)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: An explicit section about the limitations of …SciScore for 10.1101/2021.07.06.451329: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
NIH rigor criteria are not applicable to paper type.Table 2: Resources
Software and Algorithms Sentences Resources We have utilized Charmm36m forcefield in Gromacs v5 on high performance cluster (HPC) of IIT Mandi, where simulation setup was built by placing the protein structure (NSP6 91-112 and NSP6-CTR) in a cubic box with a distance of 10Å from each edge along with SPC water model and 0.15M NaCl salt concentration. Gromacssuggested: (GROMACS, RRID:SCR_014565)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
Results from scite Reference Check: We found no unreliable references.
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