Time varying association between deprivation, ethnicity and SARS-CoV-2 infections in England: A population-based ecological study
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Abstract
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SciScore for 10.1101/2021.11.09.21266054: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics not detected. Sex as a biological variable not detected. Randomization Debiased prevalence estimates are obtained as output of the methodology developed in Nicholson et al. (10) which combines PCR Pillar 2 testing data with randomised surveillance data from the Real-time Assessment of Community Transmission (REACT)3 study (11) Blinding not detected. Power Analysis not detected. Table 2: Resources
No key resources detected.
Results from OddPub: Thank you for sharing your code.
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:A limitation of our study is that the demographic data considered may not fully represent the structure of the population …
SciScore for 10.1101/2021.11.09.21266054: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics not detected. Sex as a biological variable not detected. Randomization Debiased prevalence estimates are obtained as output of the methodology developed in Nicholson et al. (10) which combines PCR Pillar 2 testing data with randomised surveillance data from the Real-time Assessment of Community Transmission (REACT)3 study (11) Blinding not detected. Power Analysis not detected. Table 2: Resources
No key resources detected.
Results from OddPub: Thank you for sharing your code.
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:A limitation of our study is that the demographic data considered may not fully represent the structure of the population at the time of analysis. For local population sizes, we used mid-year population estimates from 2020 as reference (the most up-to-date available at the time of the study), hence neglecting any changes occurring during the time of the analysis. More critically, we retrieved the proportion of BAME population from the 2011 Census (the most up to date source available at the time of the study). We work under the implicit assumption that the ethnic composition of LTLAs has not changed drastically, but we cannot verify this. Additionally, this study shows an area-level association between inequalities and SARS-CoV-2 infection burden. Given that we consider aggregated data, the analysis may suffer from ecological bias (17) (18). Our ecological framework is similar to (8) but we focus on SARS-CoV-2 infections rather than mortality and, crucially, adjusts for spatiotemporal dependence in the residuals, a necessary adjustment for obtaining correct estimates of the precision of the effect of deprivation and ethnicity (19). Additionally, while Rose et al. focus on the first wave of the pandemic (8), we consider a longer time period. Our results are consistent with other findings of higher test positivity for BAME groups, but the dynamic nature of our analysis allows us to evaluate how this effect changes during the different phases of the pandemic. Additionally, by co...
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
Results from scite Reference Check: We found no unreliable references.
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