Mental-health before and during the COVID-19 pandemic in adults with neurodevelopmental disorders

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Abstract

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  1. SciScore for 10.1101/2022.05.09.22274714: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    Ethicsnot detected.
    Sex as a biological variableSample: The Avon Longitudinal Study of Parents and Children (ALSPAC) study is an ongoing longitudinal study which recruited pregnant woman in the Avon region of South-West England, due to give birth between 1 April 1991 and 31 December 1992 (Boyd et al., 2013; Fraser et al., 2013; Northstone et al., 2019).
    Randomizationnot detected.
    Blindingnot detected.
    Power Analysisnot detected.
    Cell Line AuthenticationAuthentication: This is designed to measure hyperactive and inattentive symptoms, ranges from 0-10, and has been validated against a DSM-5 diagnosis of ADHD (Riglin et al., 2021a), with a cut-point of ≥6 recommended to capture approximately 10% of the sample.

    Table 2: Resources

    Software and Algorithms
    SentencesResources
    Statistical Analysis Procedure: All analyses were conducted in R (R Core Team, 2021)
    Statistical Analysis Procedure
    suggested: None

    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).


    Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
    For those with ADHD and females with ASD, depressive symptoms are the lowest during the first COVID timepoint, when the UK was in strictest national lockdown, with schools and many workplaces closed and limitations in place on socialising and leaving the house. Similarly, a longitudinal study in Western Australia showed that children and adolescents with ADHD reported decreases in depression and increases in positive wellbeing between pre-COVID and school closures due to the pandemic (Houghton et al., 2022). Qualitative studies in adults and children with ADHD have reported some positives of lockdown, including the flexibility of managing schedules, and less exposure to negative feedback (Ando et al., 2021; Bobo et al., 2020). Additionally, some individuals with ASD reported that the relief of day-to-day social demands was appreciated during the early lockdown, with less demands to camouflage or mask behaviour (Bundy et al., 2022). This potentially protective environment of lockdown may be particularly prevalent for females with ASD, for whom we saw the greatest decrease in depressive symptoms. Previous evidence indicates that females with ASD commonly mask or camouflage behaviours in social situations in order to ‘fit in’ (Hull et al., 2019; Hull et al., 2017) and camouflaging has been linked to greater symptoms of depression and anxiety in autistic adults (Hull et al., 2021). Therefore, it may be possible that the lack of expectation to socialise during the first COVID lock...

    Results from TrialIdentifier: No clinical trial numbers were referenced.


    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.


    Results from JetFighter: We did not find any issues relating to colormaps.


    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    Results from scite Reference Check: We found no unreliable references.


    About SciScore

    SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore checks for the presence and correctness of RRIDs (research resource identifiers), and for rigor criteria such as sex and investigator blinding. For details on the theoretical underpinning of rigor criteria and the tools shown here, including references cited, please follow this link.