A Crystallographic Snapshot of SARS-CoV-2 Main Protease Maturation Process
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SciScore for 10.1101/2020.12.23.424149: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Software and Algorithms Sentences Resources Model was refined with COOT(32) and BUSTER (33) at 1.6 Å and deposited under the code 7KFI. BUSTERsuggested: (BUSTER, RRID:SCR_015653)The melting temperature was obtained using the Boltzmann fitting on Origin Pro 9.5.1 Software (OriginLab). Originsuggested: (Origin, RRID:SCR_014212)Results from OddPub: Thank you for sharing your data.
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage …SciScore for 10.1101/2020.12.23.424149: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Software and Algorithms Sentences Resources Model was refined with COOT(32) and BUSTER (33) at 1.6 Å and deposited under the code 7KFI. BUSTERsuggested: (BUSTER, RRID:SCR_015653)The melting temperature was obtained using the Boltzmann fitting on Origin Pro 9.5.1 Software (OriginLab). Originsuggested: (Origin, RRID:SCR_014212)Results from OddPub: Thank you for sharing your data.
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We found bar graphs of continuous data. We recommend replacing bar graphs with more informative graphics, as many different datasets can lead to the same bar graph. The actual data may suggest different conclusions from the summary statistics. For more information, please see Weissgerber et al (2015).
Results from JetFighter: Please consider improving the rainbow (“jet”) colormap(s) used on pages 19 and 20. At least one figure is not accessible to readers with colorblindness and/or is not true to the data, i.e. not perceptually uniform.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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