Changes in paediatric respiratory infections at a UK teaching hospital 2016–2021; impact of the SARS-CoV-2 pandemic
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SciScore for 10.1101/2021.10.13.21264956: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics IRB: Ethical approvals: IORD has generic Research Ethics Committee, Health Research Authority and Confidentiality Advisory Group approvals (REC ref 19/SC/0403; ECC5-017(A)/2009). Sex as a biological variable not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Table 2: Resources
No key resources detected.
Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:There were limitations to this study. Respiratory diagnoses amongst ED attendees represent …
SciScore for 10.1101/2021.10.13.21264956: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics IRB: Ethical approvals: IORD has generic Research Ethics Committee, Health Research Authority and Confidentiality Advisory Group approvals (REC ref 19/SC/0403; ECC5-017(A)/2009). Sex as a biological variable not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Table 2: Resources
No key resources detected.
Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:There were limitations to this study. Respiratory diagnoses amongst ED attendees represent the more severe end of the disease spectrum and although these reflect community prevalence (this study shows similar trends to Public Health England surveillance data(39)), they likely over-represent diagnoses in the pre-school children more likely to require hospital care for respiratory infection. Furthermore, some children, for example those with croup who are not conventionally sampled, are not represented in the dataset. Changes in healthcare seeking behaviours during the pandemic impact the calculated rates of infection, however this is partly mitigated by presenting respiratory diagnoses per 1000 attendances. The increased incidence of rhinovirus, adenovirus, hCoV and parainfluenza in the pandemic relative to pre-pandemic in this study is likely exaggerated by an ascertainment bias, due to increased use of the more comprehensive Biofire respiratory pathogen panel test for deteriorating patients or those requiring aerosol generating procedures during the pandemic and introduction of quadruple Influenza A/B/RSV/SARS-CoV-2 admission screening in July 2021. Although we have divided the study period into “pandemic” and “pre-pandemic” periods, SARS-CoV-2 circulated in the UK during the early weeks of 2020, defined here as “pre-pandemic”. Since not all periods of lockdown are equivalent in terms of stringency, we used the Oxford COVID-19 government response tracker’s Stringency Index(2...
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
Results from scite Reference Check: We found no unreliable references.
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