SARS-CoV-2 infection, clinical features and outcome of COVID-19 in United Kingdom nursing homes
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SciScore for 10.1101/2020.05.19.20105460: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement Consent: 13 Verbal informed consent was sought from those individuals with mental capacity.
IRB: As such the work did not require Research Ethics Committee approval.Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
No key resources detected.
Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:This investigation had some limitations. Firstly, the non-specific nature of …
SciScore for 10.1101/2020.05.19.20105460: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement Consent: 13 Verbal informed consent was sought from those individuals with mental capacity.
IRB: As such the work did not require Research Ethics Committee approval.Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
No key resources detected.
Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:This investigation had some limitations. Firstly, the non-specific nature of COVID-19 symptoms in residents and the lack of availability of tests meant that COVID-19 had to be inferred as the cause of excess deaths in nursing homes prior to our investigation. Since symptoms are often difficult to elicit in residents and are not reliably documented in the records, symptom ascertainment for the 14 days prior to testing was likely to be incomplete. However, we made use of several sources including the residents, care home workers, GPs and records and believe that our data provide a real-life picture. We are only able to infer the role of asymptomatic care staff as potential sources of transmission based on first, staff self-isolation and sickness levels, second, the fact that bedbound residents did not leave the nursing homes and third, similarities in genome sequences of SARS-CoV-2 strains between staff and residents. We could not infer direction of transmission between the two however. A wider exploration of the role of staff was limited by lack of data including reasons for absences, resource issues and lack of compensation for staff members who were aware that if they were SARS-CoV-2 positive, they would have to self-isolate and potentially lose significant income. Our findings highlight the challenges of controlling SARS-CoV-2 outbreaks in nursing homes. Given the very high mortality observed in the care homes we investigated, this is a pressing issue. During the course of ...
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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