Airborne SARS-CoV-2 in home and hospital environments investigated with a high-powered air sampler
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SciScore for 10.1101/2021.07.16.21260337: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics IRB: The Institutional Review Board of the Franciscus Gasthuis and Vlietland Hospital in Rotterdam approved the study protocol and ethical approval was obtained (IRB protocol number 2020-092).
Consent: Written informed consent was obtained from the HCWs during the household visits.Sex as a biological variable not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Table 2: Resources
Software and Algorithms Sentences Resources Statistical analysis: All data were analyzed using Microsoft Excel and R version 3.3.2 (R Foundation for Statistical Computing). Microsoft Excelsuggested: (Microsoft Excel, RRID:SCR_016137)Results from OddPub: We did not detect open data. We …
SciScore for 10.1101/2021.07.16.21260337: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics IRB: The Institutional Review Board of the Franciscus Gasthuis and Vlietland Hospital in Rotterdam approved the study protocol and ethical approval was obtained (IRB protocol number 2020-092).
Consent: Written informed consent was obtained from the HCWs during the household visits.Sex as a biological variable not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Table 2: Resources
Software and Algorithms Sentences Resources Statistical analysis: All data were analyzed using Microsoft Excel and R version 3.3.2 (R Foundation for Statistical Computing). Microsoft Excelsuggested: (Microsoft Excel, RRID:SCR_016137)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:There are several study limitations to consider. First, the primary aim was to measure the protective effects of different types of face masks worn by infected persons to prevent further spread. In retrospect, our approach failed to address this research question due to our sampling setting with poor ventilation resulting in many positive air samples due to circulating virus RNA. Therefore, our findings should not be interpreted as a failure in the protective effects of face masks. Importantly, SARS-CoV-2 was also detected on the masks worn by the infected persons and thus these masks limited the exposition of the virus to the environment. Second, all our observations were carried out prior to the emergence of variants of concern, such as the United Kingdom, South African, and Brazilian P1 SARS-CoV-2 variants in the Netherlands. We cannot exclude that different results would have been obtained due to more transmittable variants. Third, our experimental findings in adequately ventilated ICU rooms of COVID-19 patients with low proportions of positive air samples during AGMP require confirmation in a larger cohort that should also include different oxygen therapy. In conclusion, the presented vacuum cleaner based air sampling followed by RT-qPCR is simple to perform, does not require expensive materials, and is an effective method to detect SARS-CoV-2 in the air. Although airborne transmission of SARS-CoV-2 has not yet been widely accepted, it should be considered as an importan...
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
Results from scite Reference Check: We found no unreliable references.
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