Artemisia annua L. hot-water extracts show potent activity in vitro against Covid-19 variants including delta
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SciScore for 10.1101/2021.09.08.459260: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics not detected. Sex as a biological variable not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Cell Line Authentication not detected. Table 2: Resources
Experimental Models: Cell Lines Sentences Resources Multiplicity of infection (MOI) was 0.1 as documented by (Liu et al., 2020). 2.3 Assays for determining drug inhibition of SARS-CoV-2 and cell viability: Extract dilutions were incubated for 1 h in wells of 96-well tissue culture plates containing a monolayer of Vero E6 cells seeded the prior day at 20,000 cells/well. Vero E6suggested: NoneSoftware and Algorithms Sentences Resources IC50 and IC90 values were calculated using GraphPad Prism V8.0. GraphPad Prismsuggested:…SciScore for 10.1101/2021.09.08.459260: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics not detected. Sex as a biological variable not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Cell Line Authentication not detected. Table 2: Resources
Experimental Models: Cell Lines Sentences Resources Multiplicity of infection (MOI) was 0.1 as documented by (Liu et al., 2020). 2.3 Assays for determining drug inhibition of SARS-CoV-2 and cell viability: Extract dilutions were incubated for 1 h in wells of 96-well tissue culture plates containing a monolayer of Vero E6 cells seeded the prior day at 20,000 cells/well. Vero E6suggested: NoneSoftware and Algorithms Sentences Resources IC50 and IC90 values were calculated using GraphPad Prism V8.0. GraphPad Prismsuggested: (GraphPad Prism, RRID:SCR_002798)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
Results from scite Reference Check: We found no unreliable references.
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