Outcome of Conservative Therapy in Coronavirus disease-2019 Patients Presenting With Gastrointestinal Bleeding
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SciScore for 10.1101/2020.08.06.20169813: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement Consent: Ethical clearance: In this retrospective study, the requirement of consent was waived off, and ethical approval was obtained from the Institutional Ethics Committee, All India Institute of Medical Sciences, India (Ref No: IEC-253/17.04.2020).
IACUC: Ethical clearance: In this retrospective study, the requirement of consent was waived off, and ethical approval was obtained from the Institutional Ethics Committee, All India Institute of Medical Sciences, India (Ref No: IEC-253/17.04.2020).Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Software and Algorithms Sentences Reso… SciScore for 10.1101/2020.08.06.20169813: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement Consent: Ethical clearance: In this retrospective study, the requirement of consent was waived off, and ethical approval was obtained from the Institutional Ethics Committee, All India Institute of Medical Sciences, India (Ref No: IEC-253/17.04.2020).
IACUC: Ethical clearance: In this retrospective study, the requirement of consent was waived off, and ethical approval was obtained from the Institutional Ethics Committee, All India Institute of Medical Sciences, India (Ref No: IEC-253/17.04.2020).Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Software and Algorithms Sentences Resources Data were analyzed using IBM SPSS statistical software (Version 20.0, Chicago, IL, USA). SPSSsuggested: (SPSS, RRID:SCR_002865)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:Our study has a few limitations. Small sample size, single-centre retrospective design with predominantly descriptive nature of the study are its inherent limitations. In the absence of endoscopy, we were not sure of the exact cause of UGI bleeding in all patients. We presumed all patients with cirrhosis to have portal hypertension-related bleeding. It is well known that up to 25% of patients with cirrhosis may have a non-variceal cause of bleeding. The inclusion of patients predominantly with CLD limits generalizability to other causes of bleed. We had only one patient with a LGI bleed. In conclusion, conservative management strategies including pharmacotherapy, restrictive transfusion strategy, and close hemodynamic monitoring can successfully manage GI bleeding in COVID-19 patients and reduce the need for urgent endoscopy. The decision for proceeding with endoscopy should be taken by a multidisciplinary team after consideration of the patient’s condition, response to treatment, resources and the risks involved, on a case to case basis.
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a protocol registration statement.
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