Effective presence of antibodies against common human coronaviruses in immunoglobulin medicinal products
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SciScore for 10.1101/2021.07.23.453571: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics not detected. Sex as a biological variable not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Cell Line Authentication not detected. Table 2: Resources
Experimental Models: Cell Lines Sentences Resources MRC5 cells (ATCC CCL-171™, Manassas, VA, USA) in confluent culture in 96-well microtiter plates were infected with 200 μL per well of virus/antibody mixture. MRC5suggested: ATCC Cat# CCL-171, RRID:CVCL_0440)Software and Algorithms Sentences Resources Concentration-effect curves were generated and IC50 values were calculated using a GraphPad Prism software (Version 9.1.0 for Windows, GraphPad Software, San Diego, California USA). GraphPad Prismsuggested: (GraphPad …SciScore for 10.1101/2021.07.23.453571: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics not detected. Sex as a biological variable not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Cell Line Authentication not detected. Table 2: Resources
Experimental Models: Cell Lines Sentences Resources MRC5 cells (ATCC CCL-171™, Manassas, VA, USA) in confluent culture in 96-well microtiter plates were infected with 200 μL per well of virus/antibody mixture. MRC5suggested: ATCC Cat# CCL-171, RRID:CVCL_0440)Software and Algorithms Sentences Resources Concentration-effect curves were generated and IC50 values were calculated using a GraphPad Prism software (Version 9.1.0 for Windows, GraphPad Software, San Diego, California USA). GraphPad Prismsuggested: (GraphPad Prism, RRID:SCR_002798)GraphPadsuggested: (GraphPad Prism, RRID:SCR_002798)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- No funding statement was detected.
- No protocol registration statement was detected.
Results from scite Reference Check: We found no unreliable references.
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