Critical timing and extent of public health interventions to control outbreaks dominated by SARS-CoV-2 variants in Australia: a mathematical modelling study

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Abstract

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  1. SciScore for 10.1101/2021.07.06.21260055: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    NIH rigor criteria are not applicable to paper type.

    Table 2: Resources

    Software and Algorithms
    SentencesResources
    All analyses and simulations were performed in MATLAB R 2019a (Supplementary Information p11–13).
    MATLAB
    suggested: (MATLAB, RRID:SCR_001622)

    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).


    Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
    Our study has several limitations. First, we simulated historical epidemics based on four Australian states but excluding Queensland, which experienced a significant outbreak in March–April 2020. That is because the state’s official reports did not include information on whether a diagnosed case is from a known or unknown source and hence cannot inform our model. Second, the rate of viral transmission may vary across countries due to differences in health care capacities and the extent of public health interventions. Our study uses Australia as a case study but intends to generalise this work to other settings in future investigations. Similarly, we did not consider environmental differences, which is likely to play a role and differ between states. Third, to the completion date of this study, reliable data on the transmissibility and mortality of the novel variants of SARS-CoV-2 and the effectiveness of the COVID-19 vaccine against new variants are still under investigation. Our study was conducted with limited availability of these data. Finally, we did not differentiate between the nature of the new cases. Cases in the same household as a known case and those who were isolated at the time of their diagnosis will be different from cases that are not linked to known cases and who were not isolated at the time of their diagnosis. It was not possible to incorporate these qualitative differences in a quantitative model, but they clearly matter. In conclusion, our study quantifi...

    Results from TrialIdentifier: No clinical trial numbers were referenced.


    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.


    Results from JetFighter: We did not find any issues relating to colormaps.


    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    Results from scite Reference Check: We found no unreliable references.


    About SciScore

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