Impact of reproduction number on the multiwave spreading dynamics of COVID-19 with temporary immunity: A mathematical model
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SciScore for 10.1101/2020.09.30.20204636: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
NIH rigor criteria are not applicable to paper type.Table 2: Resources
Software and Algorithms Sentences Resources We solve the equations numerically in Matlab using 2nd order Runge Kutta method with step size 0·001 day. Matlabsuggested: (MATLAB, RRID:SCR_001622)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:Some of the limitations of the present study are the natural constraints associated with any compartmental or lumped parameter model. For example, the immunity duration used in …
SciScore for 10.1101/2020.09.30.20204636: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
NIH rigor criteria are not applicable to paper type.Table 2: Resources
Software and Algorithms Sentences Resources We solve the equations numerically in Matlab using 2nd order Runge Kutta method with step size 0·001 day. Matlabsuggested: (MATLAB, RRID:SCR_001622)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:Some of the limitations of the present study are the natural constraints associated with any compartmental or lumped parameter model. For example, the immunity duration used in the model has to be an average over the entire population, which can be refined to some degree by introducing age- or vulnerability-structuring (Sandmann et. al. op. cit). When there are very few cases in a region, the lumped parameter model will no longer be valid. The actual end of the outbreak will be determined by the testing, tracing and treatment of each individual case. Another limitation arises from the current lack of knowledge regarding the human immune response to the new pathogen SARS-CoV-2. Here we have assumed two (plausible) kinds of response, one where immunity completely lapses after a given timeframe and the second where severity-reducing immunity persists indefinitely. Future work may reveal the actual immune response to be more complex than either of these assumptions. Moreover, at least six strains of SARS-CoV-2 have been identified to date (Mercatelli et. al. 2020). At present, we know little about the spreading dynamics of individual strains (Zhang et. al. 2020) and still less about the degree of cross-immunity provided by one strain against another. In this variability however also lies our model’s primary strength. The model structure makes it easy to incorporate any kind of immune response (Shayak and Mohit 2020). The computational requirement is negligible, with the run for e...
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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