Laboratory-based surveillance of COVID-19 in the Greater Helsinki area, Finland, February–June 2020

This article has been Reviewed by the following groups

Read the full article See related articles

Abstract

No abstract available

Article activity feed

  1. SciScore for 10.1101/2020.07.03.20145615: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    Institutional Review Board Statementnot detected.
    Randomizationnot detected.
    Blindingnot detected.
    Power Analysisnot detected.
    Sex as a biological variablenot detected.

    Table 2: Resources

    No key resources detected.


    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).


    Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
    As to limitations, our data did not include all tests analysed in Greater Helsinki. No clinical data were available. A bias may have been introduced by the restricted sampling criteria during March 2020. During the first weeks, control swabs were recommended for the positive cases – a policy since abandoned. Also, during the first two weeks of April less preferred oropharyngeal swabs were used due to the global shortage of nasopharyngeal swabs, which may have temporarily influenced the overall test sensitivity. Large dips in testing frequency were observed on every weekend, and also during public holidays (Figure 1). Simultaneously, the number of new positive cases dropped each time, and the epicurve (Figure 1b) may suggest that this testing deficit was not fully compensated during the following weekdays. In a response to need for large-scale testing, HUSLAB switched from two-shift work into a three-shift work on 23 March, and personnel was reallocated. A laboratory-developed test [3] was ready in use in mid-January, and testing on the cobas® 6800 system late March. Through constant global shortages on reagents and plasticware, the need to deploy several independent methods was evident to secure laboratory services and capacity building. The Amplidiag® COVID-19 tests were deployed as of mid-April, and the Novodiag® sample-to-answer test as of mid-May. In preparation for the potential next epidemic waves of COVID-19 pandemic, the difference in health-care seeking behaviours be...

    Results from TrialIdentifier: No clinical trial numbers were referenced.


    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.


    Results from JetFighter: We did not find any issues relating to colormaps.


    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    About SciScore

    SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore checks for the presence and correctness of RRIDs (research resource identifiers), and for rigor criteria such as sex and investigator blinding. For details on the theoretical underpinning of rigor criteria and the tools shown here, including references cited, please follow this link.