Estimation of global case fatality rate of coronavirus disease 2019 (COVID-19) using meta-analyses: Comparison between calendar date and days since the outbreak of the first confirmed case
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SciScore for 10.1101/2020.06.11.20128959: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
NIH rigor criteria are not applicable to paper type.Table 2: Resources
Software and Algorithms Sentences Resources For a meta-analysis of the CFR of COVID-19, MedCalc version 19.2.1 software (MedCalc Software, Ostend, Belgium, trial version) was used to analyze the summary effects with 95% confidence interval (CI) and between-study heterogeneity. MedCalcsuggested: (MedCalc, RRID:SCR_015044), Microsoft Excel version 2013 was used. Microsoft Excelsuggested: (Microsoft Excel, RRID:SCR_016137)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the …SciScore for 10.1101/2020.06.11.20128959: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
NIH rigor criteria are not applicable to paper type.Table 2: Resources
Software and Algorithms Sentences Resources For a meta-analysis of the CFR of COVID-19, MedCalc version 19.2.1 software (MedCalc Software, Ostend, Belgium, trial version) was used to analyze the summary effects with 95% confidence interval (CI) and between-study heterogeneity. MedCalcsuggested: (MedCalc, RRID:SCR_015044), Microsoft Excel version 2013 was used. Microsoft Excelsuggested: (Microsoft Excel, RRID:SCR_016137)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:The method of calculating CFR needs to be cautioned, and its limitations acknowledged. The numerator and the denominator of CFR should be composed of patients infected at the same time as those who died to accurately represent the CFR. To overcome this restraint, Baud et al.[8] and Wilson et al.[9] proposed time delay-adjusted CFR to correct the delay between confirmation and death. They adjusted the denominator of CFR as the number of confirmed cases 13-14 days before the measured date to calculate the number of confirmed cases infected concurrently to those who died. Based on these articles, researchers at Oxford University used their global COVID-19 CFR model according to the date since the outbreak in Jan 2020 [17]. However, Oxford’s calculation is also flawed since 13 to 14 days before the date of test confirmation is not necessarily the date when a subject is infected [12]. Moreover, there are cases that show test positivity even after recovery. Additionally, the stretching and overwhelming of the healthcare systems creates a delay between testing and receiving the results, thus confirming the case. As this adjusted time-delay CFR leads the estimate to an unknown bias [12, 13], we used the conventional method to calculate CFR. Moreover, the numerator of the CFR is the number of deaths with COVID-19. We should be aware that this number is imperfect, and may include deaths not directly caused by COVID-19, such as fatal comorbid diseases. This may lead to an overestimation...
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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