Global reports of takotsubo (stress) cardiomyopathy following COVID-19 vaccination: A systematic review and meta-analysis

  1. Sirwan Khalid Ahmed
  2. Mona Gamal Mohamed
  3. Rawand Abdulrahman Essa
  4. Eman Abdelaziz Ahmed Rashad Dabou
  5. Salar Omar Abdulqadir
  6. Rukhsar Muhammad Omar

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Abstract

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  1. Version published to 10.1016/j.ijcha.2022.101108
  2. Version published to 10.1101/2022.04.16.22273937v5 on medRxiv
  3. Version published to 10.1101/2022.04.16.22273937v4 on medRxiv
  4. Version published to 10.1101/2022.04.16.22273937v3 on medRxiv
  5. ScreenIT

    SciScore for 10.1101/2022.04.16.22273937: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    Ethicsnot detected.
    Sex as a biological variablenot detected.
    Randomizationnot detected.
    Blindingnot detected.
    Power Analysisnot detected.

    Table 2: Resources

    Software and Algorithms
    SentencesResources
    Search strategy: A comprehensive search of major online databases (PubMed and Google Scholar) was performed on March 10, 2022, in order to discover all articles that had been published.
    PubMed
    suggested: None
    Google Scholar
    suggested: (Google Scholar, RRID:SCR_008878)
    The data extraction process was carried out using predefined forms in Microsoft Office Excel.
    Microsoft Office Excel
    suggested: (Microsoft Excel, RRID:SCR_016137)
    Statistical analysis will be performed using the Statistical Package for the Social Sciences (SPSS) 25.0 software program (SPSS Inc, Chicago, IL, USA).
    Statistical Package for the Social Sciences
    suggested: (SPSS, RRID:SCR_002865)
    SPSS
    suggested: (SPSS, RRID:SCR_002865)

    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).

    Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
    Limitation: We recognize that our systematic review has some limitations, which include; we only involved case reports and case series, due to the limited numbers of original studies published on the takotsubo cardiomyopathy after taken COVID-19 vaccines so the results should be interpreted with some caution. Moreover, we do not have any data about the previous history of COVID-19, which may affect the results, since COVID-19 can also cause cardiac complications.

    Results from TrialIdentifier: No clinical trial numbers were referenced.

    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.

    Results from JetFighter: We did not find any issues relating to colormaps.

    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    Results from scite Reference Check: We found no unreliable references.

    About SciScore

    SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore checks for the presence and correctness of RRIDs (research resource identifiers), and for rigor criteria such as sex and investigator blinding. For details on the theoretical underpinning of rigor criteria and the tools shown here, including references cited, please follow this link.

  6. Version published to 10.1101/2022.04.16.22273937v2 on medRxiv
  7. Version published to 10.1101/2022.04.16.22273937v1 on medRxiv