RETRACTED: Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial
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SciScore for 10.1101/2020.03.16.20037135: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement Consent: Informed consent: Before being included in the study, patients meeting inclusion criteria had to give their consent to participate to the study.
IRB: The protocol, appendices and any other relevant documentation were submitted to the French National Agency for Drug Safety (ANSM) (2020-000890-25) and to the French Ethic Committee (CPP Ile de France) (20.02.28.99113) for reviewing and approved on 5th and 6th March, 2020, respectively.Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Cell Line Authentication not detected. Table 2: Resources
Experimental Models: Cell Lines Sentences Resources Cultur… SciScore for 10.1101/2020.03.16.20037135: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement Consent: Informed consent: Before being included in the study, patients meeting inclusion criteria had to give their consent to participate to the study.
IRB: The protocol, appendices and any other relevant documentation were submitted to the French National Agency for Drug Safety (ANSM) (2020-000890-25) and to the French Ethic Committee (CPP Ile de France) (20.02.28.99113) for reviewing and approved on 5th and 6th March, 2020, respectively.Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Cell Line Authentication not detected. Table 2: Resources
Experimental Models: Cell Lines Sentences Resources Culture: For all patients, 500 µL of the liquid collected from the nasopharyngeal swab were passed through 0.22-µm pore sized centrifugal filter (Merck millipore, Darmstadt, Germany), then were inoculated in wells of 96-well culture microplates, of which 4 wells contained Vero E6 cells (ATCC CRL-1586) in Minimum Essential Medium culture medium with 4% fetal calf serum and 1% glutamine. Vero E6suggested: NoneResults from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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SciScore for 10.1101/2020.03.16.20037135: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement Breastfeeding and pregnant patients were excluded Informed consent Before being included in the study , patients meeting inclusion criteria had to give their consent to participate to the study . Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable Overall , 15 patients were male ( 41.7 % ) , with a mean age of 45.1 years . Cell Line Authentication not detected. Table 2: Resources
Experimental Models: Cell Lines Sentences Resources Culture For all patients , 500 µL of the liquid collected from the nasopharyngeal swab were passed through 0.22-µm pore sized centrifugal filter ( Merck millipore , Darmstadt … SciScore for 10.1101/2020.03.16.20037135: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement Breastfeeding and pregnant patients were excluded Informed consent Before being included in the study , patients meeting inclusion criteria had to give their consent to participate to the study . Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable Overall , 15 patients were male ( 41.7 % ) , with a mean age of 45.1 years . Cell Line Authentication not detected. Table 2: Resources
Experimental Models: Cell Lines Sentences Resources Culture For all patients , 500 µL of the liquid collected from the nasopharyngeal swab were passed through 0.22-µm pore sized centrifugal filter ( Merck millipore , Darmstadt , Germany) , then were inoculated in wells of 96-well culture microplates , of which 4 wells contained Vero E6 cells ( ATCC CRL-1586 ) in Minimum Essential Medium culture medium with 4 % fetal calf serum and 1 % glutamine. Vero E6suggested: NoneResults from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
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