Atlas of ACE2 gene expression reveals novel insights into transmission of SARS-CoV-2

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1. Version published to 10.1016/j.heliyon.2020.e05850

   Jan 1, 2021
2. 

   ScreenIT

   Jun 5, 2020

   SciScore for 10.1101/2020.03.30.015644: (What is this?)

   Please note, not all rigor criteria are appropriate for all manuscripts.

   Table 1: Rigor

   Institutional Review Board Statement	not detected.
   Randomization	not detected.
   Blinding	not detected.
   Power Analysis	not detected.
   Sex as a biological variable	not detected.

   Table 2: Resources

   Software and Algorithms
   Sentences	Resources
   Latest versions of reference genomes and RefSeq gene annotations12 for these species were downloaded from NCBI (National Center for Biotechnology Information)13.	RefSeq suggested: (RefSeq, RRID:SCR_003496)
   Briefly, raw RNA-seq reads were first preprocessed to trim sequencing adapters and low-quality cycles using Ktrim software27 with default parameters; the preprocessed reads were then aligned to corresponding reference genomes using STAR software28 with default parameters.	STAR sugge…

   SciScore for 10.1101/2020.03.30.015644: (What is this?)

   Please note, not all rigor criteria are appropriate for all manuscripts.

   Table 1: Rigor

   Institutional Review Board Statement	not detected.
   Randomization	not detected.
   Blinding	not detected.
   Power Analysis	not detected.
   Sex as a biological variable	not detected.

   Table 2: Resources

   Software and Algorithms
   Sentences	Resources
   Latest versions of reference genomes and RefSeq gene annotations12 for these species were downloaded from NCBI (National Center for Biotechnology Information)13.	RefSeq suggested: (RefSeq, RRID:SCR_003496)
   Briefly, raw RNA-seq reads were first preprocessed to trim sequencing adapters and low-quality cycles using Ktrim software27 with default parameters; the preprocessed reads were then aligned to corresponding reference genomes using STAR software28 with default parameters.	STAR suggested: (STAR, RRID:SCR_015899)

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   Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).

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   Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.

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   Results from TrialIdentifier: No clinical trial numbers were referenced.

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   Results from Barzooka: We did not find any issues relating to the usage of bar graphs.

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   Results from JetFighter: We did not find any issues relating to colormaps.

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   Results from rtransparent:

   • No conflict of interest statement was detected. If there are no conflicts, we encourage authors to explicit state so.
   • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
   • No protocol registration statement was detected.

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   Read the original source
3. 

   Version published to 10.1101/2020.03.30.015644v1 on bioRxiv

   Mar 31, 2020