Decontamination of SARS-CoV-2 from cold-chain food packaging provides no marginal benefit in risk reduction to food workers

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Abstract

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  1. SciScore for 10.1101/2021.08.23.21262477: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    NIH rigor criteria are not applicable to paper type.

    Table 2: Resources

    Software and Algorithms
    SentencesResources
    The model was developed in R (version 4.0.3; R Development Core Team; Vienna, Austria) using the mc2d package for Monte Carlo simulations.50,51 For each simulation, 10,000 iterations were run.
    R Development Core
    suggested: (R Project for Statistical Computing, RRID:SCR_001905)

    Results from OddPub: Thank you for sharing your code.


    Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
    A limitation of this work is that our analysis focused on a one-hour exposure duration of the susceptible worker to contaminated plastic packaging. This duration was selected as the timing and number of products arriving in a receiving warehouse beyond one hour was unpredictable. However, when extending this to an 8-hour shift, cumulative fomite risks remained very low (handwashing and mask use: 7·5 × 10−5 [95%CI: 1·8 × 10−7-1·7 × 10−4]). A second limitation is that there are limited data on the concentration of the Delta variant shed by infected individuals, beyond the Ct value that estimates approximately 6 × 105 copies/mL in oropharyngeal swabs.83 To simulate increased infectiousness/transmissibility of Delta or other VOC, we increased infectious viral shedding among the infected workers (2-, 10-, and 100-fold), which equates to 2·4 × 106 to 2·4 × 109 infectious virus/mL of saliva. While the Delta variant should clearly fall within or below this range of increased viral shedding, this analysis can be refined as more data become available. This would also serve to reduce the uncertainty in this and other parameters which result in a dynamic range in risk estimates and confidence intervals. Using QMRA modeling, we find that susceptible workers (unvaccinated, no precautions) in frozen food packaging facilities are at low risk of SARS-CoV-2 fomite-mediated transmission (exposure to large droplets and small aerosol particles on plastic packaging) under cold-chain conditions. St...

    Results from TrialIdentifier: No clinical trial numbers were referenced.


    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.


    Results from JetFighter: We did not find any issues relating to colormaps.


    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    Results from scite Reference Check: We found no unreliable references.


    About SciScore

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