Cross-sectional cycle threshold values reflect epidemic dynamics of COVID-19 in Madagascar

  1. Soa Fy Andriamandimby
  2. Cara E. Brook
  3. Norosoa Razanajatovo
  4. Tsiry H. Randriambolamanantsoa
  5. Jean-Marius Rakotondramanga
  6. Fidisoa Rasambainarivo
  7. Vaomalala Raharimanga
  8. Iony Manitra Razanajatovo
  9. Reziky Mangahasimbola
  10. Richter Razafindratsimandresy
  11. Santatra Randrianarisoa
  12. Barivola Bernardson
  13. Joelinotahiana Hasina Rabarison
  14. Mirella Randrianarisoa
  15. Frédéric Stanley Nasolo
  16. Roger Mario Rabetombosoa
  17. Anne-Marie Ratsimbazafy
  18. Vololoniaina Raharinosy
  19. Aina H. Rabemananjara
  20. Christian H. Ranaivoson
  21. Helisoa Razafimanjato
  22. Rindra Randremanana
  23. Jean-Michel Héraud
  24. Philippe Dussart

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Abstract

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  1. Version published to 10.1016/j.epidem.2021.100533
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    SciScore for 10.1101/2021.07.06.21259473: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    NIH rigor criteria are not applicable to paper type.

    Table 2: Resources

    Experimental Models: Cell Lines
    SentencesResources
    Briefly, three SARS-CoV-2 isolates (designated hCoV-19/Madagascar/IPM-00754/2021, hCoV-19/Madagascar/IPM-01263/2021 and hCoV-19/Madagascar/IPM-01315/2021) were obtained and cultured in Vero cells as previously described [34].
    Vero
    suggested: CLS Cat# 605372/p622_VERO, RRID:CVCL_0059)
    Software and Algorithms
    SentencesResources
    Epidemic trajectories from publicly reported data: To compare our laboratory-derived epidemic growth estimates with those undertaken in real time in Madagascar, we collaborated with colleagues who recorded data on the number of new PCR-confirmed cases reported daily on national television by the Ministry of Health of the Government of Madagascar across the duration of the first epidemic wave.
    Madagascar
    suggested: (Madagascar, RRID:SCR_003274)

    Results from OddPub: Thank you for sharing your code and data.

    Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.

    Results from TrialIdentifier: No clinical trial numbers were referenced.

    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.

    Results from JetFighter: We did not find any issues relating to colormaps.

    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • No funding statement was detected.
    • No protocol registration statement was detected.

    Results from scite Reference Check: We found no unreliable references.

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  3. Version published to 10.1101/2021.07.06.21259473v1 on medRxiv