Quantifying heterogeneity in SARS-CoV-2 transmission during the lockdown in India
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SciScore for 10.1101/2020.09.10.20190017: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
NIH rigor criteria are not applicable to paper type.Table 2: Resources
No key resources detected.
Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:However, our analysis also highlight some limitations of this distribution: accounting for underlying correlations between degree and PCI can lead to different outbreak dynamics, in terms of the risk and size of major outbreaks over time (Figs. 3C,D). Our results also have implications for the efficiency of contact tracing. When a large …
SciScore for 10.1101/2020.09.10.20190017: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
NIH rigor criteria are not applicable to paper type.Table 2: Resources
No key resources detected.
Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:However, our analysis also highlight some limitations of this distribution: accounting for underlying correlations between degree and PCI can lead to different outbreak dynamics, in terms of the risk and size of major outbreaks over time (Figs. 3C,D). Our results also have implications for the efficiency of contact tracing. When a large fraction of infected individuals do not cause onward transmission, we show the value of a simple two-step strategy, of, for example, first testing family members and then testing other contacts only if at least one family member is found to be positive (Fig. 4). Such approaches can be particularly valuable in resource-constrained settings such as India, in decreasing the requirements for contact tracing substantially, while still identifying most cases. An important question, that we are not able to address using the current data, is what drives the heterogeneity in per-contact infectiousness. This heterogeneity may arise, for example, from biological factors such as the role of pre-existing, cross-reactive immunity that may moderate viral load in some individuals more effectively than others (14). Our analysis suggests that PCI increases with age and is significantly associated with sex (Fig. S5). Further data on these and other individual-level characteristics would be invaluable in further examining key risk factors for infectiousness. Where risk factors involve individual characteristics that can be readily identified in newly diagnosed pa...
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- No funding statement was detected.
- No protocol registration statement was detected.
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