A novel structure-based approach for identification of vertebrate susceptibility to SARS-CoV-2: Implications for future surveillance programmes
This article has been Reviewed by the following groups
Listed in
- Evaluated articles (ScreenIT)
Abstract
Article activity feed
-
-
SciScore for 10.1101/2022.01.10.475752: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
NIH rigor criteria are not applicable to paper type.Table 2: Resources
Software and Algorithms Sentences Resources 2.1 ACE2 Protein Sequences: The protein sequences of ACE2 orthologs (n = 356) originating from vertebrates were downloaded from NCBI protein database (5 September, 2021) (O’Leary et al., 2016). NCBIsuggested: (NCBI, RRID:SCR_006472)2.2 Evolutionary divergence of ACE2 orthologs across the vertebrates: The full set of ACE2 protein sequences originating from vertebrates were aligned using MAFFT v. MAFFTsuggested: (MAFFT, RRID:SCR_011811)7.475 (Katoh et al., 2019) and a phylogenetic tree was constructed using the Maximum Likelihood statistical method with the GTR-Gamma model in RAxML v. RAxMLsugg…SciScore for 10.1101/2022.01.10.475752: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
NIH rigor criteria are not applicable to paper type.Table 2: Resources
Software and Algorithms Sentences Resources 2.1 ACE2 Protein Sequences: The protein sequences of ACE2 orthologs (n = 356) originating from vertebrates were downloaded from NCBI protein database (5 September, 2021) (O’Leary et al., 2016). NCBIsuggested: (NCBI, RRID:SCR_006472)2.2 Evolutionary divergence of ACE2 orthologs across the vertebrates: The full set of ACE2 protein sequences originating from vertebrates were aligned using MAFFT v. MAFFTsuggested: (MAFFT, RRID:SCR_011811)7.475 (Katoh et al., 2019) and a phylogenetic tree was constructed using the Maximum Likelihood statistical method with the GTR-Gamma model in RAxML v. RAxMLsuggested: (RAxML, RRID:SCR_006086)(ab initio and homology-based hybrid methodology) (Yang et al., 2015) and Modeller (version 10.1) Modellersuggested: (MODELLER, RRID:SCR_008395)2.8 Statistical analysis: For statistical analysis, GraphPad Prism 7.01 was used (GraphPad Software, San Diego, CA). GraphPadsuggested: (GraphPad Prism, RRID:SCR_002798)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
Results from scite Reference Check: We found no unreliable references.
-
