Implementation of a pooled surveillance testing program for asymptomatic SARS-CoV-2 infections in K-12 schools and universities
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SciScore for 10.1101/2021.02.09.21251464: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics Consent: Written informed consent for Covid-19 testing was obtained from each participant from all institutions prior to the start of the surveillance program.
IRB: The SUNY Downstate Health Sciences University Institutional Review Board (IRB) reviewed and approved the study protocol (IRB #1232938-3).
Field Sample Permit: The specimen collection was performed under supervision of a trained representative from each organization.Sex as a biological variable not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Table 2: Resources
Software and Algorithms Sentences Resources Statistical Methods: Statistical analyses were performed in RStudio v1.3.959 … SciScore for 10.1101/2021.02.09.21251464: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics Consent: Written informed consent for Covid-19 testing was obtained from each participant from all institutions prior to the start of the surveillance program.
IRB: The SUNY Downstate Health Sciences University Institutional Review Board (IRB) reviewed and approved the study protocol (IRB #1232938-3).
Field Sample Permit: The specimen collection was performed under supervision of a trained representative from each organization.Sex as a biological variable not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Table 2: Resources
Software and Algorithms Sentences Resources Statistical Methods: Statistical analyses were performed in RStudio v1.3.959 (http://www.rstudio.com/), using R v4.0.2 (https://www.r-project.org/) and data visualization was performed by R package ggplot2 and ggpubr (https://rpkgs.datanovia.com/ggpubr)13,14. RStudiosuggested: (RStudio, RRID:SCR_000432)https://www.r-project.org/suggested: (R Project for Statistical Computing, RRID:SCR_001905)ggplot2suggested: (ggplot2, RRID:SCR_014601)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:One limitation of this study is that the applicability of the methodology described here requires both technical and logistical methods that are not reproducible in every lab. However, concepts of pooling, strategies around reducing costs for schools, and the unique value of providing testing for schools as it relates to community viral spread described here, remain broadly applicable to the K-12 testing strategies that are required around the country. Additional limitations include the need for lab-based testing as in theory this concept can be broadly applied to point of care concepts as well. However, as with any testing strategy, scalability is important. The ability to rapidly scale SalivaClear™ using existing lab infrastructure makes it broadly appealing to labs seeking to increase testing capacity and efficiency. While the non-standardized methods of school openings across the country are a limiting factor when evaluating the data for the exact role SalivaClear™ played for each school, it is important to highlight that all schools utilizing this method were able to remain open. In order to provide enough testing capacity to safely open schools and provide testing for at-risk communities, pooled concepts must be further evaluated and considered. As vaccination against COVID-19 may remain unavailable for children under 16 years of age for months to come, pooled testing must be considered a fundamental component to the safe reopening of schools while minimizing transmissi...
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a protocol registration statement.
Results from scite Reference Check: We found no unreliable references.
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