Unraveling the molecular basis of host cell receptor usage in SARS-CoV-2 and other human pathogenic β-CoVs
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SciScore for 10.1101/2020.08.21.260745: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
NIH rigor criteria are not applicable to paper type.Table 2: Resources
Software and Algorithms Sentences Resources Sequence dataset and multiple sequence alignment: A BLAST search was performed against the NCBI nr database using the SARS-CoV-2 spike protein (NCBI Reference Sequence: YP_009724390.1) as a query (12). BLASTsuggested: (BLASTX, RRID:SCR_001653)Cluster representatives were used to build a multiple sequence alignment (MSA) using the MAFFT software (14). MAFFTsuggested: (MAFFT, RRID:SCR_011811)The final alignment contained 135 spike protein sequences which were manually reviewed to annotate information on viral strain, host organism and cell receptors using information extracted from the NCBI … SciScore for 10.1101/2020.08.21.260745: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
NIH rigor criteria are not applicable to paper type.Table 2: Resources
Software and Algorithms Sentences Resources Sequence dataset and multiple sequence alignment: A BLAST search was performed against the NCBI nr database using the SARS-CoV-2 spike protein (NCBI Reference Sequence: YP_009724390.1) as a query (12). BLASTsuggested: (BLASTX, RRID:SCR_001653)Cluster representatives were used to build a multiple sequence alignment (MSA) using the MAFFT software (14). MAFFTsuggested: (MAFFT, RRID:SCR_011811)The final alignment contained 135 spike protein sequences which were manually reviewed to annotate information on viral strain, host organism and cell receptors using information extracted from the NCBI Protein database, UniprotKB and the literature. NCBI Proteinsuggested: (NCBI Protein, RRID:SCR_003257)UniprotKBsuggested: (UniProtKB, RRID:SCR_004426)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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