Digestive Manifestations in Patients Hospitalized With Coronavirus Disease 2019
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SciScore for 10.1101/2020.07.07.20143024: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement IRB: Institutional review board approval was obtained at each center prior to patient identification and data collection. Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Software and Algorithms Sentences Resources All analyses were conducted using SAS 9.4 (SAS Institute, Inc. Cary, North Carolina). SAS Institutesuggested: (Statistical Analysis System, RRID:SCR_008567)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the …SciScore for 10.1101/2020.07.07.20143024: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement IRB: Institutional review board approval was obtained at each center prior to patient identification and data collection. Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Software and Algorithms Sentences Resources All analyses were conducted using SAS 9.4 (SAS Institute, Inc. Cary, North Carolina). SAS Institutesuggested: (Statistical Analysis System, RRID:SCR_008567)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:The findings of this study should be interpreted in the context of several limitations, some of which are inherent to observational research on COVID-19. As highlighted above, symptom attribution and ascertainment were influenced by several factors related to conducting research during a pandemic, such as retrospective data collection and reliance on medical records review rather than direct patient interviews. Further, validated definitions for gastrointestinal symptom severity in COVID-19 are not available and thus we devised criteria that we believe reasonably reflect disease severity in terms of patient suffering and resource utilization. Alternative definitions of severity may have led to varying interpretations of the findings. Some of these limitations are mitigated by the large and geographically diverse sample, highly systematic approach to patient selection, and multi-layered and rigorous strategy to ensure the veracity of collected data. It is also important to consider that this study was restricted to hospitalized patients and thus does not reflect the prevalence and significance of digestive manifestations in outpatients with COVID-19. In summary, among patients hospitalized with COVID-19, gastrointestinal symptoms and liver test abnormalities were common, but the majority were mild in nature and their presence was not associated with worse clinical outcomes.
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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