Paired heavy- and light-chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses

Article activity feed

1. Version published to 10.1016/j.celrep.2021.109771

   Oct 1, 2021
2. 

   ScreenIT

   Jan 4, 2021

   SciScore for 10.1101/2020.12.31.424987: (What is this?)

   Please note, not all rigor criteria are appropriate for all manuscripts.

   Table 1: Rigor

   Institutional Review Board Statement	not detected.
   Randomization	not detected.
   Blinding	not detected.
   Power Analysis	not detected.
   Sex as a biological variable	not detected.
   Cell Line Authentication	not detected.

   Table 2: Resources

   Experimental Models: Cell Lines
   Sentences	Resources
   Cell line Expi293F cell was purchased from Thermo Fisher Scientific.	Expi293F suggested: RRID:CVCL_D615)
   Cell line HEK293T cell was purchased from Sino Biological.	HEK293T suggested: NCBI_Iran Cat# C498, RRID:CVCL_0063)
   Cell line Vero C1008 (Vero-E6 cell) was purchased from ATCC.	Vero C1008 suggested: ATCC Cat# CRL-1586, RRID:CVCL_0574) Vero-E6 suggested: None
   Software and Algorithms
   Sentences	Resources
   L ANALYSIS: IC50 calculations were reported …

   SciScore for 10.1101/2020.12.31.424987: (What is this?)

   Please note, not all rigor criteria are appropriate for all manuscripts.

   Table 1: Rigor

   Institutional Review Board Statement	not detected.
   Randomization	not detected.
   Blinding	not detected.
   Power Analysis	not detected.
   Sex as a biological variable	not detected.
   Cell Line Authentication	not detected.

   Table 2: Resources

   Experimental Models: Cell Lines
   Sentences	Resources
   Cell line Expi293F cell was purchased from Thermo Fisher Scientific.	Expi293F suggested: RRID:CVCL_D615)
   Cell line HEK293T cell was purchased from Sino Biological.	HEK293T suggested: NCBI_Iran Cat# C498, RRID:CVCL_0063)
   Cell line Vero C1008 (Vero-E6 cell) was purchased from ATCC.	Vero C1008 suggested: ATCC Cat# CRL-1586, RRID:CVCL_0574) Vero-E6 suggested: None
   Software and Algorithms
   Sentences	Resources
   L ANALYSIS: IC50 calculations were reported using GraphPad Prism software (version 8.4.3).	GraphPad Prism suggested: (GraphPad Prism, RRID:SCR_002798)
   Flow cytometry analysis was carried out using FlowJo software (version 10.4).	FlowJo suggested: (FlowJo, RRID:SCR_008520)

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   Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).

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   Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.

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   Results from TrialIdentifier: No clinical trial numbers were referenced.

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   Results from Barzooka: We did not find any issues relating to the usage of bar graphs.

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   Results from JetFighter: Please consider improving the rainbow (“jet”) colormap(s) used on pages 51 and 52. At least one figure is not accessible to readers with colorblindness and/or is not true to the data, i.e. not perceptually uniform.

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   Results from rtransparent:

   • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
   • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
   • No protocol registration statement was detected.

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   Read the original source
3. 

   Version published to 10.1101/2020.12.31.424987v1 on bioRxiv

   Jan 3, 2021