Psychosocial factors and hospitalisations for COVID-19: Prospective cohort study based on a community sample
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SciScore for 10.1101/2020.05.29.20100735: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement IRB: 33 In brief, baseline data collection took place between 2006 and 2010 in twenty-two research assessment centres across the UK, resulting in a sample of 502,655 people aged 40 to 69 years (response rate 5.5%).33 In UK Biobank, ethical approval was received from the North-West Multicentre Research Ethics Committee, and the research was carried out in accordance with the Declaration of Helsinki of the World Medical Association, and participants gave informed consent.
Consent: 33 In brief, baseline data collection took place between 2006 and 2010 in twenty-two research assessment centres across the UK, resulting in a sample of 502,655 people aged 40 to 69 …SciScore for 10.1101/2020.05.29.20100735: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement IRB: 33 In brief, baseline data collection took place between 2006 and 2010 in twenty-two research assessment centres across the UK, resulting in a sample of 502,655 people aged 40 to 69 years (response rate 5.5%).33 In UK Biobank, ethical approval was received from the North-West Multicentre Research Ethics Committee, and the research was carried out in accordance with the Declaration of Helsinki of the World Medical Association, and participants gave informed consent.
Consent: 33 In brief, baseline data collection took place between 2006 and 2010 in twenty-two research assessment centres across the UK, resulting in a sample of 502,655 people aged 40 to 69 years (response rate 5.5%).33 In UK Biobank, ethical approval was received from the North-West Multicentre Research Ethics Committee, and the research was carried out in accordance with the Declaration of Helsinki of the World Medical Association, and participants gave informed consent.Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable Statistical analyses: We omitted from our analyses men and women who had died before 5th March 2020 – the latest date to which vital status data were available – as they could not contribute to the risk set for COVID-19. Table 2: Resources
No key resources detected.
Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:Study strengths and limitations: The strengths of our study include it being well characterised for exposures and covariates despite its scale, allowing us to attempt to identify independent effects. That the study is prospective means assessment of these baseline data preceded that of disease onset; as such, reverse causality is not a concern such that the infection could not, for instance, influence mental health and job loss leading to downward social mobility. Our work has its weaknesses. Samples were taken from hospitalised patients but it is unclear if all cases had been exclusively hospitalised because of COVID-19-type symptoms, or, as seem likely given mass testing within hospitals, some patients were found to be positive for the infection while an inpatient for other reasons. Our outcome also represents an unfavourable response to a viral challenge as opposed to disease incidence across the full population; the latter could only be ascertained with comprehensive testing of our study sample or indeed the population of England as a whole. We excluded study members who had died prior to 5th March 2020 because they could not contribute to the risk set, however, ascertainment of hospitalisations for COVID-19 did not reliably begin until 16th March. It is unlikely, however, that the absence of vital status data for this 11 day period would have substantially biased our effect estimates in this large dataset. The UK Biobank study sample is recruited from only 5.5% of the ta...
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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