Serologic Cross-Reactivity of SARS-CoV-2 with Endemic and Seasonal Betacoronaviruses
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SciScore for 10.1101/2020.06.22.20137695: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement Consent: All clinical trial participants signed written informed consent prior to enrollment. Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Cell Line Authentication not detected. Table 2: Resources
Experimental Models: Cell Lines Sentences Resources Protein production and purification: Soluble spike trimers were produced by expression in Expi293 cells and purified by a combination of tangential flow filtration, immobilized metal affinity chromatography, and desalting, following the procedures noted in Esposito et al. Expi293suggested: RRID:CVCL_D615)Software and Algorithms Sentences Resources Data were … SciScore for 10.1101/2020.06.22.20137695: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement Consent: All clinical trial participants signed written informed consent prior to enrollment. Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Cell Line Authentication not detected. Table 2: Resources
Experimental Models: Cell Lines Sentences Resources Protein production and purification: Soluble spike trimers were produced by expression in Expi293 cells and purified by a combination of tangential flow filtration, immobilized metal affinity chromatography, and desalting, following the procedures noted in Esposito et al. Expi293suggested: RRID:CVCL_D615)Software and Algorithms Sentences Resources Data were subsequently analyzed utilizing Microsoft Excel and GraphPad Prism. Microsoft Excelsuggested: (Microsoft Excel, RRID:SCR_016137)GraphPad Prismsuggested: (GraphPad Prism, RRID:SCR_002798)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.Results from TrialIdentifier: We found the following clinical trial numbers in your paper:
Identifier Status Title NCT01386424 Recruiting Screening for LID Clinical Studies Unit Healthy Volunteer Pr… Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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