Post-intravitreal injection endophthalmitis pattern during the COVID-19 pandemic with implementation of patients’ masking

  1. Masoud Mirghorbani
  2. Fatemeh Bazvand
  3. Hamid Riazi-Esfahani
  4. Mohammadreza Mehrabi Bahar
  5. Mehdi Yaseri
  6. Mohammad Zarei

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Abstract

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  1. Version published to 10.1007/s00417-022-05726-2
  2. ScreenIT

    SciScore for 10.1101/2022.03.19.22272419: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    EthicsIRB: The study protocol was supervised and approved by the Institutional Review Board of Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran, with an ethical registration code of IR.TUMS.FARABIH.REC.1400.044.
    Sex as a biological variablenot detected.
    Randomizationnot detected.
    Blindingnot detected.
    Power Analysisnot detected.

    Table 2: Resources

    Software and Algorithms
    SentencesResources
    Statistical analysis: Statistical analysis was performed using SPSS software version 24 for windows (SPSS Inc., Chicago, IL).
    SPSS
    suggested: (SPSS, RRID:SCR_002865)

    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).

    Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
    Retrospective nature and probable clerical errors in data entry are limitations of this study. Low incidence of endophthalmitis necessitates very large study population size and multi-center collaborations to reveal potential risk factors with very small effects on the incidence of post-IVI endophthalmitis. However, such studies usually suffer from the lack of a unique, defined preparation and injection protocol among different centers that may confound the results. From this point of view, presence of a unique defined protocol before and after COVID epidemic in our tertiary center is a strength for this study. In conclusion, it seems that facial mask wearing by patients is probably not associated with an increased rate of post injection endophthalmitis and wearing these respiratory protections as a priority in respiratory epidemics such as COVID or seasonal influenza should not be a concern in this regard.

    Results from TrialIdentifier: No clinical trial numbers were referenced.

    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.

    Results from JetFighter: We did not find any issues relating to colormaps.

    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    Results from scite Reference Check: We found no unreliable references.

    About SciScore

    SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore checks for the presence and correctness of RRIDs (research resource identifiers), and for rigor criteria such as sex and investigator blinding. For details on the theoretical underpinning of rigor criteria and the tools shown here, including references cited, please follow this link.

  3. Version published to 10.1101/2022.03.19.22272419v1 on medRxiv