Epidemiological characteristics and incubation period of SARS‐CoV‐2 during the 2020–2021 winter pandemic wave in North China: An observational study

  1. Tiantian Liu
  2. Zijian Chen
  3. Jin Xu

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Abstract

As the emergence of new variants of SARS‐CoV‐2 persists across the world, it is of importance to understand the distributional behavior of the incubation period of the variants for both medical research and public health policy‐making. We collected the published individual‐level data of 941 patients of the 2020–2021 winter pandemic wave in Hebei province, North China. We computed some epidemiological characteristics of the wave and estimated the distribution of the incubation period. We further assessed the covariate effects of sex, age, and living with a case with respect to the incubation period by a model. The infection‐fatality rate was only 0.1%. The estimated median incubation period was at least 22 days, significantly extended from the estimates (ranging from 4 to 8.5 days) of the previous wave in mainland China and those ever reported elsewhere around the world. The proportion of asymptomatic patients was 90.6%. No significant covariate effect was found. The distribution of incubation period of the new variants showed a clear extension from their early generations.

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  1. Version published to 10.1002/jmv.27226
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    SciScore for 10.1101/2021.05.08.21256896: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    NIH rigor criteria are not applicable to paper type.

    Table 2: Resources

    No key resources detected.

    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).

    Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.

    Results from TrialIdentifier: No clinical trial numbers were referenced.

    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.

    Results from JetFighter: We did not find any issues relating to colormaps.

    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    Results from scite Reference Check: We found no unreliable references.

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  3. Version published to 10.1101/2021.05.08.21256896v1 on medRxiv