Rapid production of clinical‐grade SARS‐CoV‐2 specific T cells
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SciScore for 10.1101/2020.04.24.20077487: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement Consent: Eligibility criteria included age 21 to 65, a history of COVID-19 with documented positive test for SARS-CoV-2 in the past but the test had become negative since, fulfillment of all blood donation criteria per standard blood bank practices, and an informed consent with approval by the hospital Institutional Review Board (
IRB: Eligibility criteria included age 21 to 65, a history of COVID-19 with documented positive test for SARS-CoV-2 in the past but the test had become negative since, fulfillment of all blood donation criteria per standard blood bank practices, and an informed consent with approval by the hospital Institutional Review Board (Randomiza… SciScore for 10.1101/2020.04.24.20077487: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement Consent: Eligibility criteria included age 21 to 65, a history of COVID-19 with documented positive test for SARS-CoV-2 in the past but the test had become negative since, fulfillment of all blood donation criteria per standard blood bank practices, and an informed consent with approval by the hospital Institutional Review Board (
IRB: Eligibility criteria included age 21 to 65, a history of COVID-19 with documented positive test for SARS-CoV-2 in the past but the test had become negative since, fulfillment of all blood donation criteria per standard blood bank practices, and an informed consent with approval by the hospital Institutional Review Board (Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Antibodies Sentences Resources Thereafter, the cells were labeled with the Catchmatrix Reagent containing bispecific antibodies for CD45 and IFN-γ, which was secreted by the stimulated target cells during the secretion period. IFN-γsuggested: NoneResults from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.Results from TrialIdentifier: We found the following clinical trial numbers in your paper:
Identifier Status Title NCT04351659 Recruiting Novel Adoptive Cellular Therapy With SARS-CoV-2 Specific T C… Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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