Association of COVID-19 Quarantine Duration and Postquarantine Transmission Risk in 4 University Cohorts
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SciScore for 10.1101/2021.05.12.21257117: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics not detected. Sex as a biological variable not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Table 2: Resources
Software and Algorithms Sentences Resources Results are similar if we use a uniform kernel (Appendix Figure 1). 95% confidence intervals were estimated based on Agresti-Coull and calculated by the R PropCIs package (10,11). PropCIssuggested: NoneResults from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:This comparison of latent periods has …
SciScore for 10.1101/2021.05.12.21257117: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics not detected. Sex as a biological variable not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Table 2: Resources
Software and Algorithms Sentences Resources Results are similar if we use a uniform kernel (Appendix Figure 1). 95% confidence intervals were estimated based on Agresti-Coull and calculated by the R PropCIs package (10,11). PropCIssuggested: NoneResults from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:This comparison of latent periods has caveats: we have assumed 100% test sensitivity (underestimating true transmission risk); our data are biased towards young, high-socioeconomic status individuals in private universities; and conversion by RT-qPCR is tightly correlated with, but not the same as, infectiousness (9). With those caveats in mind, to limit post-quarantine transmission risk to 5% of total risk in a pre-B.1.1.7 university setting, our data suggest that quarantine with qPCR testing 1 day before intended release would need to extend to 10 days for non-strict quarantine and 7 days for strict quarantine. Most household or hotel quarantines probably more closely resemble our non-strict than strict quarantine (13,14). To achieve a post-quarantine transmission risk lower than 5% would require even longer quarantines (Figure 2). Quarantine policies need to take into account many factors including socioeconomic cost, mental health, and the effectiveness of contact tracing. For example, the overall conversion rate in a given setting depends on the effectiveness of contact tracing and the stringency of guidelines for determining “close contacts.” In our dataset, 11% of quarantined individuals convert, meaning 1.2% of those who entered quarantine converted after day 7, 0.5% after day 10 and 0.1% after day 14; these percentages are likely very different in different settings. Hence, jurisdictions should consider our measurements of latent period as one factor among several in...
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
Results from scite Reference Check: We found no unreliable references.
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