Concordance of SARS-CoV-2 Results in Self-collected Nasal Swabs vs Swabs Collected by Health Care Workers in Children and Adolescents

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Abstract

No abstract available

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  1. SciScore for 10.1101/2022.03.07.22270699: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    EthicsConsent: Ethics statement: All studies were approved by the Emory University IRB and all participants provided consent (and assent, where indicated by age) prior to participating.
    Sex as a biological variablenot detected.
    Randomizationnot detected.
    Blindingnot detected.
    Power Analysisnot detected.

    Table 2: Resources

    No key resources detected.


    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).


    Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
    There are a few limitations to the work presented. Data comparing SARS-CoV-2 detection in self-versus HCW-collected samples were limited to symptomatic participants, and there was not sufficient statistical power to detect small differences in SARS-CoV-2 detection by year of age. There was only one asymptomatic child who tested positive for SARS-CoV-2, which did result in positive results for both self- and HCW-collected samples. Further testing should be done to confirm that self-collection is effective for SARS-CoV-2 testing in an asymptomatic pediatric population. Given the similar performance of self- and HCW-collected AN swabs, data from the current study support the development of SARS-CoV-2 testing plans for school aged children that allow for self-collection. Such strategies have the potential to improve testing capacity by decreasing the need for trained staff at collection sites, and future work could evaluate the use of self-collected samples for multiplex respiratory viral testing to reduce outbreaks in this population.

    Results from TrialIdentifier: No clinical trial numbers were referenced.


    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.


    Results from JetFighter: We did not find any issues relating to colormaps.


    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    Results from scite Reference Check: We found no unreliable references.


    About SciScore

    SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore checks for the presence and correctness of RRIDs (research resource identifiers), and for rigor criteria such as sex and investigator blinding. For details on the theoretical underpinning of rigor criteria and the tools shown here, including references cited, please follow this link.