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Pharmacokinetics and pharmacogenomics of clozapine in an ancestrally diverse sample: A longitudinal analysis and GWAS using clinical monitoring data from the UK
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Transcriptome-wide Analyses of Adipose Tissue in Outbred Rats Reveal Genetic Regulatory Mechanisms Relevant for Human Obesity
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Regulation of the PKD2 Channel Function by TACAN
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Patch-seq of mouse DRG neurons reveals candidate genes for specific mechanosensory functions
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TMEM120A/TACAN inhibits mechanically activated Piezo2 channels
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The endoplasmic reticulum-resident protein TMEM-120/TMEM120A promotes fat storage in C. elegans and mammalian cells
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Cryo-EM structures of human TMEM120A and TMEM120B
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TMEM120A contains a specific coenzyme A-binding site and might not mediate poking- or stretch-induced channel activities in cells
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TMEM120 is a coenzyme A-binding membrane protein with structural similarities to ELOVL fatty acid elongase
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Genomic loci mispositioning in Tmem120a knockout mice yields latent lipodystrophy
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BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2
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TACAN is an essential component of the mechanosensitive ion channel responsible for pain sensing
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