Pharmacology and Toxicology
A list by eLife
Pharmacology and Toxicology articles that have been evaluated by eLife.
Showing page 1 of 2 pages of list content
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SntB triggers the antioxidant pathways to regulate development and aflatoxin biosynthesis in Aspergillus flavus
This article has 12 authors:This article has been curated by 1 group:Reviewed by eLife
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Activating SRC/MAPK signaling via 5-HT1A receptor contributes to the effect of vilazodone on improving thrombocytopenia
This article has 17 authors:This article has been curated by 1 group:Reviewed by eLife
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Germline cis variant determines epigenetic regulation of the anti-cancer drug metabolism gene dihydropyrimidine dehydrogenase ( DPYD )
This article has 14 authors:This article has been curated by 1 group:Reviewed by eLife
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PSTPIP2 ameliorates aristolochic acid nephropathy by suppressing interleukin-19-mediated neutrophil extracellular trap formation
This article has 14 authors:This article has been curated by 1 group:Reviewed by eLife
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Discovery and biological evaluation of a potent small molecule CRM1 inhibitor for its selective ablation of extranodal NK/T cell lymphoma
This article has 11 authors:This article has been curated by 1 group:Reviewed by eLife
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A novel triptolide analog downregulates NF-κB and induces mitochondrial apoptosis pathways in human pancreatic cancer
This article has 11 authors:This article has been curated by 1 group:Reviewed by eLife
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Death by a thousand cuts through kinase inhibitor combinations that maximize selectivity and enable rational multitargeting
This article has 6 authors:This article has been curated by 1 group:Reviewed by eLife
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Assessing drug safety by identifying the axis of arrhythmia in cardiomyocyte electrophysiology
This article has 3 authors:This article has been curated by 1 group:Reviewed by eLife
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Local generation and efficient evaluation of numerous drug combinations in a single sample
This article has 2 authors:This article has been curated by 1 group:Reviewed by eLife
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A generic binding pocket for small molecule IKs activators at the extracellular inter-subunit interface of KCNQ1 and KCNE1 channel complexes
This article has 9 authors:This article has been curated by 1 group:Reviewed by eLife
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The generation of HepG2 transmitochondrial cybrids to reveal the role of mitochondrial genotype in idiosyncratic drug-induced liver injury
This article has 6 authors:This article has been curated by 1 group:Reviewed by eLife
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Pharmacological hallmarks of allostery at the M4 muscarinic receptor elucidated through structure and dynamics
This article has 24 authors:This article has been curated by 1 group:Reviewed by eLife
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Population dynamics of immunological synapse formation induced by bispecific T cell engagers predict clinical pharmacodynamics and treatment resistance
This article has 6 authors:This article has been curated by 1 group:Reviewed by eLife
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A mechanism of uncompetitive inhibition of the serotonin transporter
This article has 10 authors:This article has been curated by 1 group:Reviewed by eLife
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Metformin protects trabecular meshwork against oxidative injury via activating integrin/ROCK signals
This article has 11 authors:This article has been curated by 1 group:Reviewed by eLife
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Modeling osteoporosis to design and optimize pharmacological therapies comprising multiple drug types
This article has 7 authors:This article has been curated by 1 group:Reviewed by eLife
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Robust and Efficient Assessment of Potency (REAP) as a quantitative tool for dose-response curve estimation
This article has 9 authors:This article has been curated by 1 group:Reviewed by eLife
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FSH-blocking therapeutic for osteoporosis
This article has 46 authors:This article has been curated by 1 group:Reviewed by eLife
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Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs
This article has 20 authors:This article has been curated by 1 group:Reviewed by eLife