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  1. Protection afforded by post-infection SARS-CoV-2 vaccine doses: a cohort study in Shanghai

    This article has 8 authors:
    1. Bo Zheng
    2. Bronner Gonçalves
    3. Pengfei Deng
    4. Weibing Wang
    5. Jie Tian
    6. xueyao Liang
    7. Ye Yao
    8. Caoyi Xue
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This valuable work by Zheng and colleagues uses a large cohort database from Shanghai to identify that post-infection vaccination among previously vaccinated individuals provides significant low to moderate protection against re-infection. The evidence supporting the conclusion is solid with some limitations, e.g., lack of symptom severity as an outcome, no inclusion of time since infection as an independent variable, improper definitions of some key variables, difficult-to-interpret figures, and exclusion of key groups (infected and then vaccinated). This study will be of interest to vaccinologists, public health officials and clinicians.

    Reviewed by eLife

    This article has 3 evaluationsAppears in 2 listsLatest version Latest activity
  2. Hybrid immunity from SARS-CoV-2 infection and vaccination in Canadian adults: cohort study

    This article has 22 authors:
    1. Patrick E. Brown
    2. Sze Hang Fu
    3. Leslie Newcombe
    4. Xuyang Tang
    5. Nico Nagelkerke
    6. H Chaim Birnboim
    7. Aiyush Bansal
    8. Karen Colwill
    9. Geneviève Mailhot
    10. Melanie Delgado-Brand
    11. Tulunay Tursun
    12. Freda Qi
    13. Anne-Claude Gingras
    14. Arthur S. Slutsky
    15. Maria D. Pasic
    16. Jeffrey Companion
    17. Isaac I. Bogoch
    18. Ed Morawski
    19. Teresa Lam
    20. Angus Reid
    21. Prabhat Jha
    22. Ab-C Study Collaborators
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This study assessed antibody levels, which are indicative of protection, resulting from both COVID-19 vaccination and natural infection in a representative sample of the Canadian population. The work provides solid evidence that Individuals who received a booster vaccination and had a prior infection had the highest antibody levels, particularly when either the vaccination or natural infection had occurred within the past six months. These findings are of fundamental importance in supporting the value of booster vaccination in populations vulnerable to severe COVID-19.

    Reviewed by eLife

    This article has 3 evaluationsAppears in 2 listsLatest version Latest activity
  3. Improving SARS-CoV-2 variants monitoring in the absence of genomic surveillance capabilities: a serological study in Bolivian blood donors in October 2021 and June 2022

    This article has 16 authors:
    1. Lucia Inchauste
    2. Elif Nurtop
    3. Lissete Bautista Machicado
    4. Yanine Leigue Roth
    5. Shirley Lenz Gonzales
    6. Maria Luisa Herrera
    7. Katty Mina Villafan
    8. Pedro Mamani Mamani
    9. Marcelo Ramos Espinoza
    10. Juan Carlos Pavel Suarez
    11. Juan Cansio Garcia Copa
    12. Yitzhak Leigue Zabala
    13. Etzel Arancibia Cardozo
    14. Pierre Gallian
    15. Xavier de Lamballerie
    16. Stéphane Priet
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This important study examines SARS-CoV-2 seroprevalence in Bolivia and aims to provide insights into the transmission of the virus and the effects of vaccination on population immunity. However, the evidence for the main claims is incomplete because of the uncertainties about the accuracy of the neutralization assays given the cross-neutralization present across variants, as well as the selected population of blood donors tested. These uncertainties need to be addressed to support the premise of the paper.

    Reviewed by eLife

    This article has 3 evaluationsAppears in 2 listsLatest version Latest activity
  4. Disentangling the relationship between cancer mortality and COVID-19 in the US

    This article has 3 authors:
    1. Chelsea L. Hansen
    2. Cécile Viboud
    3. Lone Simonsen
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This valuable work explores death coding data to understand the impact of COVID-19 on cancer mortality. The work provides solid evidence that deaths with cancer as a contributing cause were not above what would be expected during pandemic waves, suggesting that cancer did not strongly increase the risk of dying of COVID-19. These results are an interesting exploration into the coding of causes of death that can be used to make sense of how deaths are coded during a pandemic in the presence of other underlying diseases, such as cancer.

    Reviewed by eLife

    This article has 3 evaluationsAppears in 2 listsLatest version Latest activity
  5. Antigenic drift and subtype interference shape A(H3N2) epidemic dynamics in the United States

    This article has 26 authors:
    1. Amanda C Perofsky
    2. John Huddleston
    3. Chelsea Hansen
    4. John R Barnes
    5. Thomas Rowe
    6. Xiyan Xu
    7. Rebecca Kondor
    8. David E Wentworth
    9. Nicola Lewis
    10. Lynne Whittaker
    11. Burcu Ermetal
    12. Ruth Harvey
    13. Monica Galiano
    14. Rodney Stuart Daniels
    15. John W McCauley
    16. Seiichiro Fujisaki
    17. Kazuya Nakamura
    18. Noriko Kishida
    19. Shinji Watanabe
    20. Hideki Hasegawa
    21. Sheena G Sullivan
    22. Ian G Barr
    23. Kanta Subbarao
    24. Florian Krammer
    25. Trevor Bedford
    26. Cécile Viboud
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This paper explores the relationships among evolutionary and epidemiological quantities in influenza, and presents fundamental findings that substantially advance our understanding of the drivers of influenza epidemics. The authors use a rich set of data sources to gather and analyze compelling evidence on the roles of genetic distance, other influenza dynamics and epidemiological indicators in predicting influenza epidemics. The central findings highlight the significant influence of genetic distance on A(H3N2) virus epidemiology and emphasize the role of A(H1N1) virus incidence in shaping A(H3N2) epidemics, suggesting subtype interference as a key factor. This paper also makes relevant data available to the research community.

    Reviewed by eLife

    This article has 4 evaluationsAppears in 2 listsLatest version Latest activity
  6. Higher ratio of plasma omega-6/omega-3 fatty acids is associated with greater risk of all-cause, cancer, and cardiovascular mortality: A population-based cohort study in UK Biobank

    This article has 7 authors:
    1. Yuchen Zhang
    2. Yitang Sun
    3. Qi Yu
    4. Suhang Song
    5. J Thomas Brenna
    6. Ye Shen
    7. Kaixiong Ye
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      The manuscript provides convincing evidence that both circulating omega-6 and omega-3 PUFAs are associated with lower all-cause, cancer, and cardiovascular mortality in the UK BioBank population and that omega-3s have a stronger effect than omega-6s. The findings have important public health implications.

    Reviewed by eLife

    This article has 7 evaluationsAppears in 2 listsLatest version Latest activity
  7. Design of the HPV-automated visual evaluation (PAVE) study: Validating a novel cervical screening strategy

    This article has 19 authors:
    1. Silvia de Sanjosé
    2. Rebecca B Perkins
    3. Nicole Campos
    4. Federica Inturrisi
    5. Didem Egemen
    6. Brian Befano
    7. Ana Cecilia Rodriguez
    8. Jose Jerónimo
    9. Li C Cheung
    10. Kanan Desai
    11. Paul Han
    12. Akiva P Novetsky
    13. Abigail Ukwuani
    14. Jenna Marcus
    15. Syed Rakin Ahmed
    16. Nicolas Wentzensen
    17. Jayashree Kalpathy-Cramer
    18. Mark Schiffman
    19. On behalf of the PAVE Study Group
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This important study will provide evidence about a novel screen-triage-treat strategy for cervical cancer prevention. The trial will generate convincing evidence regarding the efficacy, effectiveness, cost-effectiveness, feasibility and acceptability in a range of geographically spread low-resource settings. The strategy should contribute to improving access to cervical cancer prevention to vulnerable women with low access to health care, and, therefore, at the highest risk of cervical cancer.

    Reviewed by eLife

    This article has 13 evaluationsAppears in 2 listsLatest version Latest activity
  8. Effect of an enhanced public health contact tracing intervention on the secondary transmission of SARS-CoV-2 in educational settings: The four-way decomposition analysis

    This article has 14 authors:
    1. Olivera Djuric
    2. Elisabetta Larosa
    3. Mariateresa Cassinadri
    4. Silvia Cilloni
    5. Eufemia Bisaccia
    6. Davide Pepe
    7. Laura Bonvicini
    8. Massimo Vicentini
    9. Francesco Venturelli
    10. Paolo Giorgi Rossi
    11. Patrizio Pezzotti
    12. Alberto Mateo Urdiales
    13. Emanuela Bedeschi
    14. The Reggio Emilia Covid-19 Working Group
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This study provides a potentially useful assessment of the effect of testing contacts of cases in school classes when identified, rather than at the end of quarantine, on both the number of secondary infections and other outcomes including tracing delay and identification of the possible source of infection. The authors find that the intervention likely led to a decrease in tracing delay and an increase in the number of possible sources of infection, though were unable to determine whether secondary transmission decreased, due in part to unmeasured confounding. While the surveillance system described provides a solid dataset appropriate for this analysis, the description of methods, study outcomes, and consideration of potential confounding factors is incomplete.

    Reviewed by eLife

    This article has 4 evaluationsAppears in 2 listsLatest version Latest activity
  9. A modelled analysis of the impact of COVID-19-related disruptions to HPV vaccination

    This article has 6 authors:
    1. Louiza S Velentzis
    2. Megan A Smith
    3. James Killen
    4. Julia ML Brotherton
    5. Rebecca Guy
    6. Karen Canfell
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      The study presents important findings for public health authorities and policymakers to enable them to make evidence-based decisions when deciding on how to manage the effect of HPV vaccination disruptions. This study is particularly relevant in light of the efforts of the WHO to achieve global elimination of cervical cancers. The findings are convincing and the model used is appropriate.

    Reviewed by eLife

    This article has 4 evaluationsAppears in 2 listsLatest version Latest activity
  10. Cervical cancer screening improvements with self-sampling during the COVID-19 pandemic

    This article has 3 authors:
    1. Miriam Elfström
    2. Penelope Grace Gray
    3. Joakim Dillner
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This paper is of interest to researchers and policy makers involved in cervical cancer prevention. The paper provides insight into how the Covid19 pandemic accelerated changes in organized cervical cancer screening. The claim that self-sampling led to a major improvement of test coverage seems somewhat exaggerated and alternative hypotheses to those provided by the authors on the population who chose self-sampling are possible. Nonetheless, this is a valuable piece of work given the scope of the intervention(s) and the precedent it sets i.e. a crisis can in fact accelerate positive changes in screening that have been academic possibilities rather than practical realities.

    Reviewed by eLife

    This article has 5 evaluationsAppears in 2 listsLatest version Latest activity
  11. Risk of second primary cancers after a diagnosis of first primary cancer: A pan-cancer analysis and Mendelian randomization study

    This article has 8 authors:
    1. Xiaohao Ruan
    2. Da Huang
    3. Yongle Zhan
    4. Jingyi Huang
    5. Jinlun Huang
    6. Ada Tsui-Lin Ng
    7. James Hok-Leung Tsu
    8. Rong Na
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This study presents a valuable finding on the associations and causal relationship between second primary cancers and the initial diagnosis of a primary cancer via using a large database. The evidence supporting the claims of the authors is solid. The work will be of interest to cancer clinicians.

    Reviewed by eLife

    This article has 3 evaluationsAppears in 2 listsLatest version Latest activity
  12. Identifying metabolic features of colorectal cancer liability using Mendelian randomization

    This article has 22 authors:
    1. Caroline Bull
    2. Emma Hazelwood
    3. Joshua A Bell
    4. Vanessa Tan
    5. Andrei-Emil Constantinescu
    6. Carolina Borges
    7. Danny Legge
    8. Kimberley Burrows
    9. Jeroen R Huyghe
    10. Hermann Brenner
    11. Sergi Castellvi-Bel
    12. Andrew T Chan
    13. Sun-Seog Kweon
    14. Loic Le Marchand
    15. Li Li
    16. Iona Cheng
    17. Rish K Pai
    18. Jane C Figueiredo
    19. Neil Murphy
    20. Marc J Gunter
    21. Nicholas J Timpson
    22. Emma E Vincent
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      The manuscript by Bull et al provides valuable information on the relationship between metabolic features, in particular different lipoproteins and fatty acids, and colorectal cancer. They use solid methods and combine different data sources to analyze forward and reverse Mendelian Randomizations that support their claims.

    Reviewed by eLife

    This article has 6 evaluationsAppears in 2 listsLatest version Latest activity
  13. Understanding disruptions in cancer care to reduce increased cancer burden

    This article has 8 authors:
    1. Kia L Davis
    2. Nicole Ackermann
    3. Lisa M Klesges
    4. Nora Leahy
    5. Callie Walsh-Bailey
    6. Sarah Humble
    7. Bettina Drake
    8. Vetta L Sanders Thompson
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      The study presents patterns of cancer care disruption in southern Illinois and eastern Missouri in the summer of 2020. Survey results show factors that impact cancer care during the COVID-19 pandemic, including group differences by race. The important findings provide solid evidence about variation in cancer care disruptions and opportunities to improve return to care.

    Reviewed by eLife

    This article has 4 evaluationsAppears in 2 listsLatest version Latest activity
  14. Modeling resource allocation strategies for insecticide-treated bed nets to achieve malaria eradication

    This article has 8 authors:
    1. Nora Schmit
    2. Hillary M Topazian
    3. Matteo Pianella
    4. Giovanni D Charles
    5. Peter Winskill
    6. Michael T White
    7. Katharina Hauck
    8. Azra C Ghani
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This study presents a valuable finding on the optimal prioritization in different malaria transmission settings for the distribution of insecticide-treated nets to reduce the malaria burden. The evidence supporting the claims of the authors is solid. The work will be of interest from a global funder perspective, though somewhat less relevant for individual countries.

    Reviewed by eLife

    This article has 8 evaluationsAppears in 3 listsLatest version Latest activity
  15. Nationwide mammography screening participation in Denmark during the COVID-19 pandemic: An observational study

    This article has 7 authors:
    1. Tina Bech Olesen
    2. Henry Jensen
    3. Henrik Møller
    4. Jens Winther Jensen
    5. Berit Andersen
    6. Ilse Vejborg
    7. Sisse H Njor
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This article is of broad interest to public health researchers and to health policymakers in populations with national screening programs. It provides important knowledge on the impact of the COVID-19 pandemic on participation in mammography screening in Denmark by socio-economic indicators. The study provides convincing evidence for how the pandemic exacerbated disparities in breast cancer screening in Denmark.

    Reviewed by eLife

    This article has 4 evaluationsAppears in 2 listsLatest version Latest activity
  16. A rapid review of COVID-19’s global impact on breast cancer screening participation rates and volumes from January to December 2020

    This article has 7 authors:
    1. Reagan Lee
    2. Wei Xu
    3. Marshall Dozier
    4. Ruth McQuillan
    5. Evropi Theodoratou
    6. Jonine Figueroa
    7. On Behalf of UNCOVER and the International Partnership for Resilience in CancerSystems (I-PaRCS), Breast Cancer Working Group 2
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This study presents important evidence of the impact of the covid pandemic on breast cancer screening globally but with important variations by healthcare setting. The data analysis is comprehensive, using solid systematic review methods. The results will be of interest to public health policymakers and health care and cancer control practitioners and researchers across the globe.

    Reviewed by eLife

    This article has 3 evaluationsAppears in 2 listsLatest version Latest activity
  17. Healthcare in England was affected by the COVID-19 pandemic across the pancreatic cancer pathway: A cohort study using OpenSAFELY-TPP

    This article has 14 authors:
    1. Agnieszka Lemanska
    2. Colm Andrews
    3. Louis Fisher
    4. Seb Bacon
    5. Adam E Frampton
    6. Amir Mehrkar
    7. Peter Inglesby
    8. Simon Davy
    9. Keith Roberts
    10. Praveetha Patalay
    11. Ben Goldacre
    12. Brian MacKenna
    13. The OpenSAFELY Collaborative
    14. Alex J Walker
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This study provides useful information on the impact of the pandemic on the quantity of healthcare delivered to patients with pancreatic cancer in England. The authors showed that there was no difference in the number of diagnoses of pancreatic cancer during the pandemic compared to the preceding 5-year period, but a reduction in surgical resections by nearly 25%. They reported no difference in deaths between the two periods. They show no differences in rates of diagnosis, but the clinical relevance is incomplete as they have not compared survival from cancer between those time periods.

    Reviewed by eLife

    This article has 3 evaluationsAppears in 2 listsLatest version Latest activity
  18. Sleep regularity and mortality: a prospective analysis in the UK Biobank

    This article has 7 authors:
    1. Lachlan Cribb
    2. Ramon Sha
    3. Stephanie Yiallourou
    4. Natalie A Grima
    5. Marina Cavuoto
    6. Andree-Ann Baril
    7. Matthew P Pase
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This manuscript provides fundamental findings on the association between sleep regularity and mortality in the UK Biobank, which is a popular topic in recent sleep and circadian research in population-based studies. The study is based on a large accelerometer study with validated follow-up of incident diseases and deaths, and the data quality and large sample size are convincing and strengthen the credibility of the conclusion. This will be of wide interest to researchers in the sleep study field, epidemiologists, practicing clinicians and the general public.

    Reviewed by eLife

    This article has 7 evaluationsAppears in 2 listsLatest version Latest activity
  19. Global diversity and antimicrobial resistance of typhoid fever pathogens: Insights from a meta-analysis of 13,000 Salmonella Typhi genomes

    This article has 115 authors:
    1. Megan E Carey
    2. Zoe A Dyson
    3. Danielle J Ingle
    4. Afreenish Amir
    5. Mabel K Aworh
    6. Marie Anne Chattaway
    7. Ka Lip Chew
    8. John A Crump
    9. Nicholas A Feasey
    10. Benjamin P Howden
    11. Karen H Keddy
    12. Mailis Maes
    13. Christopher M Parry
    14. Sandra Van Puyvelde
    15. Hattie E Webb
    16. Ayorinde Oluwatobiloba Afolayan
    17. Anna P Alexander
    18. Shalini Anandan
    19. Jason R Andrews
    20. Philip M Ashton
    21. Buddha Basnyat
    22. Ashish Bavdekar
    23. Isaac I Bogoch
    24. John D Clemens
    25. Kesia Esther da Silva
    26. Anuradha De
    27. Joep de Ligt
    28. Paula Lucia Diaz Guevara
    29. Christiane Dolecek
    30. Shanta Dutta
    31. Marthie M Ehlers
    32. Louise Francois Watkins
    33. Denise O Garrett
    34. Gauri Godbole
    35. Melita A Gordon
    36. Andrew R Greenhill
    37. Chelsey Griffin
    38. Madhu Gupta
    39. Rene S Hendriksen
    40. Robert S Heyderman
    41. Yogesh Hooda
    42. Juan Carlos Hormazabal
    43. Odion O Ikhimiukor
    44. Junaid Iqbal
    45. Jobin John Jacob
    46. Claire Jenkins
    47. Dasaratha Ramaiah Jinka
    48. Jacob John
    49. Gagandeep Kang
    50. Abdoulie Kanteh
    51. Arti Kapil
    52. Abhilasha Karkey
    53. Samuel Kariuki
    54. Robert A Kingsley
    55. Roshine Mary Koshy
    56. AC Lauer
    57. Myron M Levine
    58. Ravikumar Kadahalli Lingegowda
    59. Stephen P Luby
    60. Grant Austin Mackenzie
    61. Tapfumanei Mashe
    62. Chisomo Msefula
    63. Ankur Mutreja
    64. Geetha Nagaraj
    65. Savitha Nagaraj
    66. Satheesh Nair
    67. Take K Naseri
    68. Susana Nimarota-Brown
    69. Elisabeth Njamkepo
    70. Iruka N Okeke
    71. Sulochana Putli Bai Perumal
    72. Andrew J Pollard
    73. Agila Kumari Pragasam
    74. Firdausi Qadri
    75. Farah N Qamar
    76. Sadia Isfat Ara Rahman
    77. Savitra Devi Rambocus
    78. David A Rasko
    79. Pallab Ray
    80. Roy Robins-Browne
    81. Temsunaro Rongsen-Chandola
    82. Jean Pierre Rutanga
    83. Samir K Saha
    84. Senjuti Saha
    85. Karnika Saigal
    86. Mohammad Saiful Islam Sajib
    87. Jessica C Seidman
    88. Jivan Shakya
    89. Varun Shamanna
    90. Jayanthi Shastri
    91. Rajeev Shrestha
    92. Sonia Sia
    93. Michael J Sikorski
    94. Ashita Singh
    95. Anthony M Smith
    96. Kaitlin A Tagg
    97. Dipesh Tamrakar
    98. Arif Mohammed Tanmoy
    99. Maria Thomas
    100. Mathew S Thomas
    101. Robert Thomsen
    102. Nicholas R Thomson
    103. Siaosi Tupua
    104. Krista Vaidya
    105. Mary Valcanis
    106. Balaji Veeraraghavan
    107. François-Xavier Weill
    108. Jackie Wright
    109. Gordon Dougan
    110. Silvia Argimón
    111. Jacqueline A Keane
    112. David M Aanensen
    113. Stephen Baker
    114. Kathryn E Holt
    115. Global Typhoid Genomics Consortium Group Authorship
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      Although largely descriptive, this meta-analysis of 13,000 published Typhi genomes is hugely important to public health. The dataset and presented analysis represents the first wholesale analysis of all available Typhi genomes from the last 21 years. The findings are of great significance to tracking the emergence and maintenance of AMR in Typhi and include novel insights into XDR strain emergence in Pakistan as well as the relationship between MDR maintenance and chromosomal integration.

    Reviewed by eLife

    This article has 4 evaluationsAppears in 3 listsLatest version Latest activity
  20. The impact of COVID-19 on cancer screening and treatment in older adults: The Multiethnic Cohort Study

    This article has 6 authors:
    1. Victoria P Mak
    2. Kami White
    3. Lynne R Wilkens
    4. Iona Cheng
    5. Christopher A Haiman
    6. Loic Le Marchand
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      The authors used the Multiethnic Cohort (MEC) study to study how COVID-19 impacted access to cancer screenings and treatment. This study's important findings served to identify key factors associated with cancer-related screening and healthcare-seeking during the pandemic. This investigation provides solid evidence to inform future policies, particularly in older and vulnerable populations.

    Reviewed by eLife

    This article has 2 evaluationsAppears in 2 listsLatest version Latest activity