Factor XI localization in human deep venous thrombus and function of activated factor XI on venous thrombus formation and hemostasis

  1. Nobuyuki Oguri
  2. Toshihiro Gi
  3. Eriko Nakamura
  4. Kazunari Maekawa
  5. Eiji Furukoji
  6. Hoshimi Okawa
  7. Sho Kouyama
  8. Saki Horiuchi
  9. Akira Sawaguchi
  10. Tatefumi Sakae
  11. Minako Azuma
  12. Yujiro Asada
  13. Atsushi Yamashita

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Abstract

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  1. Version published to 10.1016/j.rpth.2025.102720
  2. preLights

    Excerpt

    Could blood thinners be made safer? This study explores targeting Factor XI to prevent dangerous clots like DVT and pulmonary embolism—avoiding the bleeding risks of current treatments

  3. Version published to 10.1101/2023.09.19.558346v1 on bioRxiv